Persina I S, Kalamkarian A A, Zabanova E V, Averbakh E V
Arkh Patol. 1990;52(3):20-5.
On the basis of clinico-morphological analysis of 104 patients with malignant skin lymphomas (MSL) they are subdivided into two groups: epidermotropic (mycosis fungoides, prolymphocytic and lymphoblastic MSL with sinuous nuclei, histiocytic MSL) and non-epidermotropic (prolymphocytic MSL with roundish nuclei, microlymphoblastic and immunoblastic MSL). The former group differs from the latter by the involvement of the epidermis, with hyperplasia of keratinocytes and the disturbance of their differentiation, penetration of tumour cell into the epidermis and by the composition, type and localization of the proliferate. Epidermotropic MSL were much more frequent, affected younger persons, had a longer duration, more widespread skin involvement with polymorphic eruptions. Non-epidermotropic MSL were characterised by the appearance of single tumours of the skin and early generalization.
基于对104例皮肤恶性淋巴瘤（MSL）患者的临床形态学分析，将其分为两组：亲表皮性（蕈样肉芽肿、核呈迂曲状的原淋巴细胞性和淋巴母细胞性MSL、组织细胞性MSL）和非亲表皮性（核呈圆形的原淋巴细胞性MSL、微淋巴母细胞性和免疫母细胞性MSL）。前一组与后一组的不同之处在于表皮受累情况，表现为角质形成细胞增生及其分化紊乱、肿瘤细胞侵入表皮，以及增殖的组成、类型和定位。亲表皮性MSL更为常见，累及较年轻人群，病程较长，皮肤受累范围更广且有多种皮疹。非亲表皮性MSL的特征是出现单个皮肤肿瘤且早期发生播散。
