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异种移植牛心包补片修复心内缺损的短期和中期结果:一项单中心研究的最终结果

Short- and mid-term results of xenograft-bovine pericardial patch in the repair of intracardiac defects: final results of a single-centre study.

作者信息

Yaliniz Hafize, Salih Orhan K, Atalay Atakan, Keklik Vecih, Gocen Ugur, Topcuoglu Mehmet S, Guzel Yasin, Basturk Yuksel, Aslan Mehmet, Erdem Sevcan, Poyrazoglu Hakan

机构信息

1 Department of Cardiovascular Surgery, Faculty of Medicine, University of Cukurova, Saricam, Adana, Turkey.

2 Department of Pediatric Cardiology, Faculty of Medicine, University of Cukurova, Saricam, Adana, Turkey.

出版信息

Cardiol Young. 2014 Jun;24(3):510-4. doi: 10.1017/S1047951113000711. Epub 2013 May 22.

DOI:10.1017/S1047951113000711
PMID:23694855
Abstract

INTRODUCTION

A variety of patch materials have been used in the repair of intracardiac defects. We evaluated the short- and mid-term clinical and echocardiography results of glutaraldehyde-preserved bovine pericardium patches used to repair intracardiac defects in our clinic.

METHODS AND RESULTS

This study examines the short- (up to 30 days post-operatively) and mid-term (up to 24 months post-operatively) results of 533 patients with intracardiac defects who underwent surgical correction with glutaraldehyde-preserved bovine pericardium patches between 2004 and 2010 at a university clinic. Short- and mid-term post-operative echocardiographic studies showed no evidence of calcification, thrombus, or aneurysmal dilatation on the patch. Vegetation developed in two (0.37%) of the 533 patients.

CONCLUSION

These results that have been obtained from a group of large number of patients imply that the glutaraldehyde-preserved bovine pericardium patches may be preferable in the closure of cardiac defects because of their low complication rates and ease of use.

摘要

引言

多种补片材料已用于心内缺损的修复。我们评估了在我们诊所使用戊二醛保存的牛心包补片修复心内缺损的短期和中期临床及超声心动图结果。

方法与结果

本研究考察了2004年至2010年间在一所大学诊所接受戊二醛保存的牛心包补片手术矫正的533例心内缺损患者的短期(术后30天内)和中期(术后24个月内)结果。术后短期和中期超声心动图研究显示补片上无钙化、血栓或动脉瘤样扩张迹象。533例患者中有2例(0.37%)出现赘生物。

结论

从一组大量患者中获得的这些结果表明,戊二醛保存的牛心包补片因其低并发症发生率和使用方便,可能是关闭心脏缺损的首选材料。

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Short- and mid-term results of xenograft-bovine pericardial patch in the repair of intracardiac defects: final results of a single-centre study.异种移植牛心包补片修复心内缺损的短期和中期结果:一项单中心研究的最终结果
Cardiol Young. 2014 Jun;24(3):510-4. doi: 10.1017/S1047951113000711. Epub 2013 May 22.
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