基底型偏头痛患者对拉莫三嗪有反应：5 年随访。

Basilar-type migraine patients responsive to lamotrigine: a 5-year follow-up.

机构信息

Department of Neuroscience, Institute of Clinical Neurophysiology, Azienda Ospedaliero-Universitaria, Ospedali Riuniti, Foggia, Italy.

出版信息

Neurol Sci. 2013 May;34 Suppl 1:S165-6. doi: 10.1007/s10072-013-1384-y.

DOI:10.1007/s10072-013-1384-y

PMID:23695071

Abstract

Five years ago we reported the case of three patients affected by basilar-type migraine (BM) responsive to lamotrigine. At that time, proven treatment options for BM are rather limited and lamotrigine has been tested in BM patients because it was a widely tested treatment for migraine with aura. That positive 1-year experience leaded us to suggest that lamotrigine could be a preventive therapeutic option for BM patients, with and without menstruation association. We now report the five-year follow-up of the same patients to confirm and underlie the possible role of lamotrigine to induce BM attacks remission.

摘要

五年前，我们报告了三例基底型偏头痛（BM）患者对拉莫三嗪有反应的病例。当时，BM 的治疗方法相当有限，而拉莫三嗪已在 BM 患者中进行了测试，因为它是一种广泛测试的有先兆偏头痛的治疗方法。这一积极的 1 年经验使我们认为，拉莫三嗪可能是有或无月经相关的 BM 患者的一种预防治疗选择。我们现在报告了相同患者的 5 年随访结果，以确认和强调拉莫三嗪诱导 BM 发作缓解的可能作用。