Department of Otorhinolaryngology-Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA.
Int Forum Allergy Rhinol. 2013 Sep;3(9):712-7. doi: 10.1002/alr.21178. Epub 2013 May 20.
A retrospective data analysis at a university tertiary referral center was conducted to characterize the natural history, clinical characteristics, management principles, and outcomes of paranasal sinus mucoceles.
A chart review was performed on 102 patients with a total of 133 paranasal sinus mucoceles who were treated between 1987 and 2011 at the Hospital of the University of Pennsylvania.
The study population included patients with a mean age of 53.1 years (range, 22-82 years). Patients were diagnosed with a mucocele on average 5.3 years following prior functional endoscopic sinus surgery (FESS), 17.7 years following prior paranasal sinus trauma, and 18.1 years following prior open sinus surgery. The most common presenting symptoms were headache (42.1%) and maxillofacial pressure (28.6%). The most common sites were the frontal, frontoethmoidal, and ethmoid sinuses. Fifty-seven mucoceles (44.9%) had intraorbital extension, intracranial extension, or both. Out of 133 mucoceles, 114 underwent ESS without complication.
The length of time between prior surgery or trauma and mucocele presentation highlights the importance of long-term follow-up in both patient care and in the understanding and reporting of surgical outcomes. In this study, most patients exhibited nonspecific symptomatology despite extensive mucoceles and a significant incidence of orbital and skull-base erosion. The endoscopic approach can be safely used for the management of such lesions.
在一所大学的三级转诊中心进行了回顾性数据分析,以描述鼻窦黏液囊肿的自然病史、临床特征、治疗原则和结果。
对 1987 年至 2011 年间在宾夕法尼亚大学医院接受治疗的 102 例共 133 例鼻窦黏液囊肿患者进行了病历回顾。
研究人群的平均年龄为 53.1 岁(范围 22-82 岁)。患者平均在功能性内镜鼻窦手术(FESS)后 5.3 年、鼻窦外伤后 17.7 年和鼻窦开放手术后 18.1 年被诊断为黏液囊肿。最常见的症状是头痛(42.1%)和面部压力(28.6%)。最常见的部位是额窦、额筛窦和筛窦。57 例黏液囊肿(44.9%)有眶内或颅内扩展或两者皆有。在 133 例黏液囊肿中,114 例经 ESS 治疗无并发症。
既往手术或外伤与黏液囊肿出现之间的时间间隔强调了长期随访在患者护理以及对手术结果的理解和报告中的重要性。在本研究中,尽管黏液囊肿广泛存在且有相当大的眶内和颅底骨质侵蚀,但大多数患者表现出非特异性症状。内镜方法可安全用于此类病变的治疗。