Gold J E, Schwam L, Castella A, Pike S B, Opfell R, Zalusky R
Department of Medicine, Beth Israel Medical Center, Mount Sinai School of Medicine, New York, NY 10003.
Cancer. 1990 Jul 15;66(2):363-8. doi: 10.1002/1097-0142(19900715)66:2<363::aid-cncr2820660227>3.0.co;2-j.
The development of malignant neoplasms in patients with the acquired immune deficiency syndrome (AIDS) or with a positive human immunodeficiency virus (HIV) antibody test is a well known phenomenon. According to the guidelines from the Centers for Disease Control (Atlanta, GA), the presence of intermediate-grade or high-grade B-cell non-Hodgkin's lymphoma in HIV antibody-positive patients is considered a diagnostic criterion for AIDS. The authors describe two cases of malignant plasma cell tumors in two young HIV-infected patients. In light of this and other reports of plasma cell tumors in patients at risk for AIDS or with a positive HIV antibody test, the finding of another manifestation of B-cell neoplasia in these patients may enlarge the spectrum of AIDS-related tumors.
获得性免疫缺陷综合征（AIDS）患者或人类免疫缺陷病毒（HIV）抗体检测呈阳性者发生恶性肿瘤是一种众所周知的现象。根据疾病控制中心（佐治亚州亚特兰大）的指南，HIV抗体阳性患者中存在中等级别或高级别B细胞非霍奇金淋巴瘤被视为AIDS的诊断标准。作者描述了两名年轻HIV感染患者发生恶性浆细胞瘤的病例。鉴于此以及其他有关处于AIDS风险患者或HIV抗体检测呈阳性患者发生浆细胞瘤的报告，在这些患者中发现B细胞肿瘤形成的另一种表现形式可能会扩大与AIDS相关肿瘤的范围。
