Minov Jordan B, Karadzinska-Bislimovska Jovanka D, Vasilevska Kristin V, Stoleski Saso B, Mijakoski Dragan G
Department for Respiratory Functional Diagnostics, Institute for Occupational Health of R. Macedonia, Skopje, The Former Yugoslav Republic of Macedonia.
Arch Environ Occup Health. 2013;68(4):235-42. doi: 10.1080/19338244.2012.701249.
In order to assess prevalence and characteristics of exercise-related respiratory symptoms (ERRS) and exercise-induced bronchoconstriction (EIB) in industrial bakery, the authors performed a cross-sectional study including 57 bakers and an equal number of office workers studied as a control. Evaluation of examined subjects included completion of a questionnaire, skin prick tests to common inhalant and occupational allergens, spirometry, and exercise and histamine challenge. The authors found a similar prevalence of ERRS and EIB in both bakers and controls. EIB was significantly associated with atopy, asthma, family history of asthma, and positive histamine challenge in either group, whereas in bakers it was closely related to sensitization to occupational allergens (p = .032). Bronchial reaction to exercise was significantly higher in bakers with EIB (25.7% vs 19.2%; p = .021). These findings suggest that occupational exposure in industrial bakery may accentuate bronchoconstrictive response to exercise.
为了评估工业烘焙业中与运动相关的呼吸道症状（ERRS）和运动诱发的支气管收缩（EIB）的患病率及特征，作者开展了一项横断面研究，纳入了57名面包师，并选取了同等数量的办公室职员作为对照进行研究。对受试对象的评估包括填写问卷、针对常见吸入性和职业性过敏原进行皮肤点刺试验、肺功能测定以及运动和组胺激发试验。作者发现，面包师和对照组中ERRS和EIB的患病率相似。EIB与特应性、哮喘、哮喘家族史以及两组中组胺激发试验阳性显著相关，而在面包师中，它与对职业性过敏原的致敏密切相关（p = 0.032）。有EIB的面包师对运动的支气管反应显著更高（25.7% 对19.2%；p = 0.021）。这些发现表明，工业烘焙业中的职业暴露可能会加剧对运动的支气管收缩反应。
