Kristof M
Fyziologický ústav CSAV, Praha.
Cesk Neurol Neurochir. 1990 May;53(3):156-63.
Views on the termination of long-term antiepileptic treatment differ. The submitted paper emphasizes the importance of a correctly established prognosis for assessment of a suitable time for the termination of therapy. The correct prognosis can be established on the basis of the mutual ratio of favourable and unfavourable prognostic factors in the course of every individual case of the disease. The aim of the work made in a group of 105 patients with epilepsy was to assess the prognostic values of 31 factors which play an important role in the course of the disease. The author found statistically significant differences in the incidence of some factors in patient groups with a favourable and adverse course of the disease. In the conclusion the author describes the tactics of terminating antiepileptic treatment based on the assessed prognostic factors.
对于长期抗癫痫治疗的终止,观点各异。所提交的论文强调了正确制定预后对于评估合适的治疗终止时间的重要性。正确的预后可根据疾病每一个体病例过程中有利和不利预后因素的相互比例来确定。对105例癫痫患者进行研究的目的是评估31个在疾病过程中起重要作用的因素的预后价值。作者发现,在疾病进程良好和不良的患者组中,某些因素的发生率存在统计学上的显著差异。在结论中,作者根据评估出的预后因素描述了终止抗癫痫治疗的策略。