Faculty of Medical Sciences, The University of the West Indies, St Michael, Barbados.
Lupus. 2013 Jun;22(7):736-9. doi: 10.1177/0961203313490243. Epub 2013 May 22.
Cutaneous squamous cell carcinoma, the second most common form of non-melanotic skin cancer, may develop in long-standing discoid lesions, especially those that are depigmented and located in sun-exposed areas. The clinical course of this complication may be aggressive, with early metastases and a risk of mortality. We report three cases demonstrating this emerging trend of secondary squamous cell carcinoma in discoid lesions as the incidence of this secondary malignancy in other diseased skin lesions is on the decline.
皮肤鳞状细胞癌是第二常见的非黑色素瘤性皮肤癌，可能在长期存在的盘状病变中发展，特别是那些色素减退和位于暴露于阳光下的区域的病变。这种并发症的临床过程可能具有侵袭性，早期转移和死亡风险。我们报告了三例病例，表明盘状病变中的继发性鳞状细胞癌呈这种新兴趋势，因为其他病变皮肤中的这种继发性恶性肿瘤的发病率正在下降。
