Multiple squamous cell carcinomas in lesions of discoid lupus erythematosus.

Squamous cell carcinoma (SCC) is the most common skin cancer in black patients. In half of the cases, it is associated with predisposing factors. We present a patient who has been evaluated for thirty-nine years with a diagnosis of discoid lupus erythematosus (DLE) and has multiple SCCs. The lesions occurred in chronic hyperkeratotic lesions of DLE.