Leuzzi Giovanni, Cesario Alfredo, Margaritora Stefano, Parisi Anna Mariantonia, Porziella Venanzio, Meacci Elisa, Vita Maria Letizia, Congedo Maria Teresa, Chiappetta Marco, Granone Pierluigi
Ann Ital Chir. 2013 Mar-Apr;84(2):193-5.
Skeletal muscle metastasis is a very rare event in patients with oesophageal cancer. We herein report and discuss a case of a 65 years old man with history of gastro-esophageal reflux disease referred to our department for pyrosis associated to persistent low back pain. Oesophageal endoscopy and transesophageal endo-sonography showed a tumour localized in the lower third of the esophagus, histologically proved to be adenocarcinoma. Clinical staging procedures detected a two centimetres vascularized nodular lesion placed into right para-vertebral muscles at the level of L4 as the only sign of potential distant disease (versus a differential diagnosis of primitive sarcoma). The muscle lesion was completely removed and confirmed as secondary adenocarcinoma. Due to this evidence a chemotherapy protocol was initiated. After nine months the patient underwent transhiatal oesophagectomy. To the best of our knowledge this is the first reported case of a soft tissue metastasis from oesophageal cancer resected with radical intent.
骨骼肌转移在食管癌患者中是非常罕见的情况。我们在此报告并讨论一例65岁男性患者,该患者有胃食管反流病病史,因烧心伴持续性腰痛转诊至我科。食管内镜检查和经食管超声内镜检查显示肿瘤位于食管下三分之一处,组织学证实为腺癌。临床分期检查发现一个两厘米大小的血管化结节性病变,位于L4水平的右侧椎旁肌肉,这是潜在远处疾病的唯一迹象(与原发性肉瘤的鉴别诊断)。肌肉病变被完全切除并证实为继发性腺癌。基于这一证据,启动了化疗方案。九个月后,患者接受了经裂孔食管切除术。据我们所知,这是首例有根治性切除意图的食管癌软组织转移报告病例。