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法国西南部癫痫疾病调查。I. 癫痫综合征的发病率。

Survey of seizure disorders in the French southwest. I. Incidence of epileptic syndromes.

作者信息

Loiseau J, Loiseau P, Guyot M, Duche B, Dartigues J F, Aublet B

机构信息

Department of Neurology, University Hospital, Bordeaux, France.

出版信息

Epilepsia. 1990 Jul-Aug;31(4):391-6. doi: 10.1111/j.1528-1157.1990.tb05493.x.

DOI:10.1111/j.1528-1157.1990.tb05493.x
PMID:2369875
Abstract

An epidemiologic survey began on March 1, 1984, and ended on February 28, 1985. During this period, all neurologists and electroencephalographers of the department of Gironde, an administrative district of the French Southwest (1,128,164 residents in 1982) obtained information by questionnaire from all persons who had experienced an epileptic seizure for the first time in their lives. Recurrent, isolated, and situation-related seizures were included. Febrile convulsions and neonatal seizures were excluded. The global incidence rate of diagnosed epileptic seizures was 71.3/100,000. The incidence rates per year and per 100,000 persons by type of epileptic syndrome were 1.7 for idiopathic and 13.6 for symptomatic localization-related epilepsies, 5.6 for idiopathic and 1.1 for symptomatic generalized epilepsies, 1.9 for undermined epilepsies, 29.0 for situation-related seizures, 18.3 for isolated seizures, and 0.3 for television epilepsies. Other epileptic syndromes were not represented. Using a classification of epileptic syndromes and not of epileptic seizures reduces difficulties in an epidemiologic survey. Diagnosis of an epileptic syndrome is time dependent, however, and at follow-up some patients shift from one group to another.

摘要

一项流行病学调查于1984年3月1日开始,1985年2月28日结束。在此期间,法国西南部行政区吉伦特省(1982年有1,128,164名居民)的所有神经科医生和脑电图检查人员通过问卷调查收集了所有首次经历癫痫发作患者的信息。复发性、孤立性和情境相关性发作均包括在内。热性惊厥和新生儿惊厥被排除在外。确诊癫痫发作的总体发病率为71.3/10万。按癫痫综合征类型划分,每年每10万人的发病率分别为:特发性癫痫综合征为1.7,症状性局灶性相关性癫痫为13.6;特发性全身性癫痫为5.6,症状性全身性癫痫为1.1;不明类型癫痫为1.9;情境相关性发作29.0;孤立性发作18.3;电视性癫痫0.3。未涵盖其他癫痫综合征。采用癫痫综合征而非癫痫发作的分类方法可减少流行病学调查中的困难。然而,癫痫综合征的诊断取决于时间,在随访过程中,一些患者会从一组转变为另一组。

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