[喉颗粒细胞瘤的诊断与治疗]
[Diagnosis and management of granular cell tumor of the larynx].
作者信息
Lv Dan, Liu Shixi, Yu Rong, Zhu Yuanzhi, Yang Hui
机构信息
Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
出版信息
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Feb;27(3):116-8.
OBJECTIVE
To investigate the histogenesis, morphological features and biologic behaviors of granular cell tumor(GCT) of the larynx.
METHOD
A retrospective study was performed in three cases of GCT in our hospital, the clinical data were studied with histopathologic analysis, histochemical and immunohistochemical staining, and combining with the analysis of domestic and foreign literatures.
RESULT
Histopathologic features of laryngeal GCT were identical to that in soft tissues, but pseudoepitheliomatous hyperplasia was present in 50%-60% cases of the tumor. This disease may originate from the neurogenic Schwann cell, S-100 could be positive in immunohistochemistry.
CONCLUSION
Laryngeal GCT is a rare benign tumor and can be cured by local excision.
目的
探讨喉颗粒细胞瘤（GCT）的组织发生、形态学特征及生物学行为。
方法
对我院3例GCT患者进行回顾性研究，结合临床资料进行组织病理学分析、组织化学及免疫组织化学染色，并结合国内外文献分析。
结果
喉GCT的组织病理学特征与软组织者相同，但50% - 60%的肿瘤病例存在假上皮瘤样增生。该疾病可能起源于神经源性施万细胞，免疫组织化学中S - 100可呈阳性。
结论
喉GCT是一种罕见的良性肿瘤，局部切除可治愈。
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