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[12例头颈部颗粒细胞瘤的临床特征及文献复习]

[Clinical characteristics and literature review of 12 cases of granulosa cell tumor of head and neck].

作者信息

Chen Xuejun, Feng Lifei, Yin Gaofei, Li Pingdong, Zhong Qi, Fang Jugao, Zhang Yang

机构信息

Department of Otorhinolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Key Laboratory of Otolaryngology Head and Neck Surgery,Ministry of Education,Beijing,100730,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Aug;36(8):625-629. doi: 10.13201/j.issn.2096-7993.2022.08.012.

Abstract

To investigate the clinical and pathological features, treatment, prognostic and its influence factors of granulosa cell tumor of head and neck. The clinical medical records of 12 patients with head and neck granulosa cell tumor confirmed by pathology for diagnosis and treatment in Beijing Tongren Hospital affiliated to Capital Medical University were reviewed and collected. The follow-up durations were 4-57 months, with a median of 23 months. The origination of twelve cases were reviewed: 3 cases of the vocal cords, 2 cases of the retroannular region, 1 cases of the ventricular bands, 1 cases of the interarytenoid region, 1 cases of the paraglottic space, 1 cases of the epiglottis, 1 cases of the soft palate, 1 cases of the ventricle of larynx, 1 cases of the trapezius muscle. All 12 patients were undergoing surgical treatment in our hospital, including one who had postoperative adjuvant radiotherapy after second operation. Granulosa cell tumor occurs in the head and neck, usually a benign tumor with diverse morphology, and its diagnosis is mainly based on tumor histopathological examination. Surgical local excision is used in most cases, especially minimally invasive surgery is recommended, with lower postoperative recurrence rate and better prognosis.

摘要

探讨头颈部颗粒细胞瘤的临床病理特征、治疗方法、预后及其影响因素。回顾并收集首都医科大学附属北京同仁医院经病理确诊并接受诊治的12例头颈部颗粒细胞瘤患者的临床病历资料。随访时间为4 - 57个月,中位随访时间为23个月。回顾12例病例的发病部位:声带3例,环后区2例,室带1例,杓间区1例,声门旁间隙1例,会厌1例,软腭1例,喉室1例,斜方肌1例。12例患者均在我院接受手术治疗,其中1例在二次手术后接受了术后辅助放疗。头颈部颗粒细胞瘤通常为良性肿瘤,形态多样,其诊断主要依靠肿瘤组织病理学检查。多数情况下采用手术局部切除,尤其推荐微创手术,术后复发率较低,预后较好。

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本文引用的文献

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Granular Cell Tumor in Auditory Meatus: A Case Report.外耳道颗粒细胞瘤 1 例报告。
Ear Nose Throat J. 2024 Feb;103(2):87-89. doi: 10.1177/01455613211038234. Epub 2021 Aug 23.
6
Granular cell tumour: malignant or benign?颗粒细胞瘤:恶性还是良性?
Singapore Med J. 2015 Sep;56(9):513-7. doi: 10.11622/smedj.2015136.
9
[Diagnosis and management of granular cell tumor of the larynx].[喉颗粒细胞瘤的诊断与治疗]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Feb;27(3):116-8.
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Malignant granular cell tumor: a look into the diagnostic criteria.恶性颗粒细胞瘤:诊断标准探讨。
Pathol Res Pract. 2011 Mar 15;207(3):164-8. doi: 10.1016/j.prp.2010.12.007. Epub 2011 Feb 1.

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