Cancer Metastasis Alert and Prevention Center, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350002, China.
Curr Drug Metab. 2013 Jun;14(5):616-23. doi: 10.2174/13892002113149990003.
In Traditional Chinese Medicine (TCM), ginseng roots are taken orally as a pharmacological adaptogen and nourishing stimulants for thousands of years. Along with the rapid advancement of modern life technologies, ginseng's effects as a non-toxic non-organ-specific cancer preventive agent have recently been elucidated both at molecular levels and on clinical aspects. Here we presented some techniques used for separating ginseng active ingredients, evidence of effects of ginseng and its ingredients on cancer and cancer metastasis obtained from in vitro and in vivo experiments and thousands of volunteers participated in various clinical trials. As a biological response modifier and an adaptogen to synergistically enhance efficacy of conventional therapy as a supplement, adequate ginseng consumption reduces the risk of development of all types of cancer and the recurrence of some types of cancer, improves host intrinsic response to cancer and quality of patients' life. We also briefly stated recent case reports on potential interaction between warfarin and ginseng products.
在中医（TCM）中，人参根被口服作为一种药理学的适应原和滋补兴奋剂已有数千年的历史。随着现代生活技术的快速发展，人参作为一种无毒的非器官特异性癌症预防剂的作用最近在分子水平和临床方面得到了阐明。在这里，我们介绍了一些用于分离人参活性成分的技术，以及人参及其成分对癌症和癌症转移的影响的证据，这些证据来自体外和体内实验以及数千名志愿者参加的各种临床试验。作为一种生物反应调节剂和适应原，可以协同增强常规治疗的疗效作为补充，适量食用人参可以降低各种癌症的发展风险和某些类型癌症的复发风险，提高宿主对癌症的固有反应和患者的生活质量。我们还简要说明了最近关于华法林和人参产品之间潜在相互作用的案例报告。
