Kachur Karina, Suntres Zacharias E
a Department of Biology , Lakehead University , Thunder Bay , Ontario , Canada P7B 5E1.
b Medical Sciences Division , Northern Ontario School of Medicine , Thunder Bay , Ontario , Canada P7B 5E1.
Expert Rev Anti Infect Ther. 2016;14(1):81-94. doi: 10.1586/14787210.2016.1118345. Epub 2015 Dec 2.
Ginseng is commonly used in traditional Chinese medicine as a tonic and an adaptogen to reduce fatigue and boost the immune system. In recent years, ginseng extracts are shown to have both bacteriostatic and bactericidal actions and seem to exert their effects by several mechanisms, including disruption of biofilms, inhibition of quorum-sensing and virulence factors, and altering motility. Also, ginseng extracts are shown to have antifungal properties as demonstrated by their ability to inhibit the growth of several mold and yeast species. Extracts from ginseng root have a strong antiviral activity against the RNA viruses in cell cultures and animal models. In addition to the antimicrobial activities, ginseng extracts are shown to possess immunomodulatory properties involved in the amelioration of infections. The present paper describes the antimicrobial effects of ginseng and its extracts.
人参在传统中医中常用作滋补剂和适应原,以减轻疲劳和增强免疫系统。近年来,人参提取物已显示出具有抑菌和杀菌作用,并且似乎通过多种机制发挥其作用,包括破坏生物膜、抑制群体感应和毒力因子以及改变运动性。此外,人参提取物已显示出具有抗真菌特性,这通过它们抑制几种霉菌和酵母菌种生长的能力得到证明。人参根提取物在细胞培养和动物模型中对RNA病毒具有强大的抗病毒活性。除了抗菌活性外,人参提取物还显示出具有参与改善感染的免疫调节特性。本文描述了人参及其提取物的抗菌作用。