代偿性睾丸肥大男孩血浆促黄体生成素和促卵泡生成素对促性腺激素释放激素的反应。

Plasma LH and FSH response to LRH in boys with compensatory testicular hypertrophy.

作者信息

Laron Z, Dickerman Z, Prager-Lewin R, Keret R, Halabe E

出版信息

J Clin Endocrinol Metab. 1975 Jun;40(6):977-81. doi: 10.1210/jcem-40-6-977.

Abstract

The plasma LH, FSH and testosterone response to LRH was studied in 12 boys with compensatory testicular hypertrophy (CTH) and normal puberty and in a matched control group with normal testicular development. It was found, that the boys with CTH had normal basal plasma testosterone and LH concentrations; at the same time the basal plasma FSH level were significantly higher than in the control group. The response of plasma LH and FSH to LRH was markedly greater in the CTH group than it was in the control group. It is concluded, that the contralateral testicular hypertrophy which enables a normal pubertal process is the result of increased secretion of gonadotropins, mainly FSH.

摘要

对12名患有代偿性睾丸肥大（CTH）且青春期正常的男孩以及睾丸发育正常的匹配对照组男孩，研究了血浆促黄体生成素（LH）、促卵泡生成素（FSH）和睾酮对促性腺激素释放激素（LRH）的反应。结果发现，患有CTH的男孩血浆睾酮和LH基础浓度正常；同时，血浆FSH基础水平显著高于对照组。CTH组血浆LH和FSH对LRH的反应明显大于对照组。得出结论，使青春期发育正常的对侧睾丸肥大是促性腺激素，主要是FSH分泌增加的结果。