Sisson R
School of Nursing, University of California, San Francisco 94143-0610.
Heart Lung. 1990 Jul;19(4):373-8.
This descriptive study was a pilot effort to determine the effect of specific sensory input on the cortical activity of a selected population of young adults with a closed head injury. The specific research questions were (1) Does the comatose patient demonstrate a response on an electroencephalogram (EEG) to a specific auditory stimulus? (2) Does the comatose patient demonstrate other types of responses to a specific auditory stimulus? The subjects were three male and two female young adults 15 to 29 years of age who had a closed head injury as the result of an automobile accident. A similarity in depth of coma was established by using the Glasgow Coma Scale. Cortical activity was recorded by EEG at the same time that auditory stimulation was introduced to the subject. Data obtained by observation during the period of EEG recording were also included by an additional measure of the subject's response to stimulation. The findings indicate that persons in a coma do respond to auditory stimulation. The responses were varied in this small sample, but some type of response did occur. Two patients demonstrated a response on EEG and the other responded by eye opening or extremity movement. The EEG alone does not appear to be useful as a measure of response to auditory stimulus. Further work needs to be done to determine what other methods measure the response of comatose patients to auditory stimulation.
这项描述性研究是一项初步尝试，旨在确定特定感觉输入对选定的一群闭合性颅脑损伤年轻成年人皮质活动的影响。具体研究问题如下：（1）昏迷患者在脑电图（EEG）上是否对特定听觉刺激有反应？（2）昏迷患者对特定听觉刺激是否有其他类型的反应？研究对象是三名男性和两名女性年轻成年人，年龄在15至29岁之间，他们因汽车事故而遭受闭合性颅脑损伤。通过使用格拉斯哥昏迷量表确定昏迷深度的相似性。在向受试者引入听觉刺激的同时，通过脑电图记录皮质活动。在脑电图记录期间通过观察获得的数据也包括对受试者刺激反应的额外测量。研究结果表明，昏迷患者确实会对听觉刺激做出反应。在这个小样本中，反应各不相同，但确实出现了某种类型的反应。两名患者在脑电图上有反应，另一名患者通过睁眼或肢体运动做出反应。仅脑电图似乎不能作为衡量对听觉刺激反应的有用指标。需要进一步开展工作以确定还有哪些其他方法可测量昏迷患者对听觉刺激的反应。
