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有意识和无意识姑息治疗患者中语音刺激的生理效应——一项试点研究

Physiologic effects of voice stimuli in conscious and unconscious palliative patients-a pilot study.

作者信息

Buchholz Kerstin, Liebl Patrick, Keinki Christian, Herth Natalie, Huebner Jutta

机构信息

Working Group Integrative Oncology, Dr. Senckenberg Chronomedical Institute, J.W. Goethe University, Frankfurt/Main, Germany.

Medizinische Klinik II, Hämatologie und Onkologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.

出版信息

Wien Med Wochenschr. 2018 May;168(7-8):204-208. doi: 10.1007/s10354-018-0622-6. Epub 2018 Feb 19.

DOI:10.1007/s10354-018-0622-6
PMID:29460262
Abstract

BACKGROUND

Sounds and acoustic stimuli can have an effect on human beings. In medical care, sounds are often used as parts of therapies, e. g., in different types of music therapies. Also, human speech greatly affects the mental status. Although calming sounds and music are widely established in the medical field, clear evidence for the effect of sounds in palliative care is scare, and data about effects of the human voice in general are still missing. Thus, the aim of this study was to evaluate the effects of different voice stimuli on palliative patients.

METHODS

Two different voice stimuli (one calm, the other turbulent) were presented in a randomized sequence, and physiological parameters (blood pressure, heart frequency, oxygen saturation, respiratory rate) were recorded.

RESULTS

Twenty patients (14 conscious and 6 unconscious) participated in this study. There was a decrease of heart frequency as well as an increase of oxygen saturation in the group of conscious patients, whereas no significant change of blood pressure or respiratory rate were detected in either group, conscious and unconscious patients.

CONCLUSIONS

Although our dataset is heterogeneous, it can be concluded that voice stimuli can influence conscious patients. However, in this setting, no effect on unconscious patients was demonstrated. More clinical research on this topic with larger groups and a broader spectrum of parameters is needed.

摘要

背景

声音和声学刺激会对人类产生影响。在医疗护理中,声音常被用作治疗的一部分,例如在不同类型的音乐治疗中。此外,人类的言语也会极大地影响精神状态。尽管舒缓的声音和音乐在医学领域已被广泛应用,但关于声音在姑息治疗中作用的明确证据却很匮乏,而且关于人类声音总体影响的数据仍然缺失。因此,本研究的目的是评估不同声音刺激对姑息治疗患者的影响。

方法

以随机顺序呈现两种不同的声音刺激(一种舒缓,另一种嘈杂),并记录生理参数(血压、心率、血氧饱和度、呼吸频率)。

结果

20名患者(14名意识清醒,6名无意识)参与了本研究。意识清醒的患者组心率下降,血氧饱和度升高,而意识清醒和无意识患者组的血压或呼吸频率均未检测到显著变化。

结论

尽管我们的数据集具有异质性,但可以得出声音刺激会影响意识清醒患者的结论。然而,在这种情况下,未证明对无意识患者有影响。需要对该主题进行更多涉及更大样本量和更广泛参数范围的临床研究。

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