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漏斗胸闭式修复对心肺状况的长期影响。

Longer term effects of closed repair of pectus excavatum on cardiopulmonary status.

机构信息

Department of Pediatric Surgery, Alberta Children's Hospital, University of Calgary, Calgary, Alberta, Canada T3B 6A8.

出版信息

J Pediatr Surg. 2013 May;48(5):1049-54. doi: 10.1016/j.jpedsurg.2013.02.024.

Abstract

BACKGROUND

The "Nuss" repair is done for correction of moderate to severe pectus excavatum (PE). The long term cardiopulmonary and psychosocial effects of repair are uncertain. The objective of this study was to compare cardiopulmonary function and subjective evaluation of appearance and exercise tolerance pre-bar insertion with post-bar removal.

METHODS

All patients underwent preoperative and post-bar (3 month) removal evaluation with complete pulmonary function tests, exercise stress testing, echocardiogram, and self-rated appearance and exercise tolerance scoring. The protocol was approved by the regional ethics board, and all families gave informed consent.

RESULTS

Sixty-seven patients underwent pre and post testing. Preoperative CT index was 4.4 ± 1.3. Cardiopulmonary outcomes, standardized for height and weight, showed significant improvements in FEV-1 as (pre) 81.1 ± 17.0 vs post 89.8 ± 20.5*, FVC: 91.2 ± 18.6 vs 98.9 ± 22.9*, O2 pulse: 75.8 ± 14.4 vs 80.5 ± 18.3* (each as % predicted). Both the self-ratings of appearance (2.5 ± 0.8 vs 4.4 ± 0.5) and ability to exercise (3.3 ± 0.7 vs 4.3 ± 0.6, scale 1-5) increased significantly. (All data: mean ± St Dev, *p<0.05) CONCLUSIONS: Closed repair of PE results in improvements in pulmonary and aerobic exercise function and perceived appearance and exercise tolerance. Our data suggest that the impact on appearance and self-perceived well being is greater than the physical effect.

摘要

背景

“Nuss”修复术用于矫正中度至重度漏斗胸(PE)。修复后的长期心肺和社会心理影响尚不确定。本研究的目的是比较术前插入和术后取出支撑杆前后心肺功能以及对外观和运动耐量的主观评估。

方法

所有患者均接受术前和术后(3 个月)评估,包括完整的肺功能检查、运动应激测试、超声心动图以及自我评估的外观和运动耐量评分。该方案获得了地区伦理委员会的批准,所有家属均签署了知情同意书。

结果

67 例患者接受了术前和术后检查。术前 CT 指数为 4.4±1.3。心肺功能结果,按身高和体重标准化后,FEV-1 显著改善(术前)81.1±17.0 与术后 89.8±20.5*,FVC:91.2±18.6 与术后 98.9±22.9*,O2 脉搏:75.8±14.4 与术后 80.5±18.3*(均为预测值的百分比)。自我评估的外观(2.5±0.8 与 4.4±0.5)和运动能力(3.3±0.7 与 4.3±0.6,评分 1-5)均显著提高。(所有数据:均值±St Dev,*p<0.05)。

结论

PE 的闭合修复可改善肺和有氧运动功能以及感知到的外观和运动耐量。我们的数据表明,对外观和自我感知的幸福感的影响大于身体上的影响。

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