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除囊性纤维化患者外,广泛存在伯克霍尔德菌。

An outbreak of Burkholderia multivorans beyond cystic fibrosis patients.

机构信息

Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic.

出版信息

J Hosp Infect. 2013 Jul;84(3):248-51. doi: 10.1016/j.jhin.2013.04.001. Epub 2013 May 22.

DOI:10.1016/j.jhin.2013.04.001
PMID:23706672
Abstract

Strains of the Burkholderia cepacia complex (Bcc) are opportunistic pathogens capable of causing serious infection in cystic fibrosis patients. Recently we identified a suspected outbreak of infection with Bcc strains at the University Hospital Olomouc. Seventy-four Bcc strains were isolated from 52 patients, most of whom (N = 48) did not suffer from cystic fibrosis. Most frequently (N = 46) Burkholderia multivorans was isolated and 24 (52.2%) of these strains were clonal. Fifteen of these strains were isolated from intensive care patients, five of whom died from hospital-acquired pneumonia. B. multivorans can cause serious outbreaks of infection beyond cystic fibrosis sufferers.

摘要

伯克霍尔德氏菌复合群(Bcc)菌株是一种机会性病原体,能够导致囊性纤维化患者发生严重感染。最近,我们在奥洛穆茨大学医院发现了一起疑似 Bcc 菌株感染爆发事件。从 52 名患者中分离出 74 株 Bcc 菌株,其中大多数(N=48)患者没有患囊性纤维化。最常分离到的是伯克霍尔德氏菌(N=46),其中 24 株(52.2%)为克隆株。这些菌株中有 15 株从重症监护病房的患者中分离出来,其中 5 例因医院获得性肺炎而死亡。B. multivorans 可引起囊性纤维化患者以外的严重感染爆发。

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