Division of Epidemiology, Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, GA, USA.
J Affect Disord. 2013 Sep 5;150(2):350-5. doi: 10.1016/j.jad.2013.04.017. Epub 2013 May 21.
Failure to control for the confounding effects from body perceptions may contribute to the inconsistency of literature on the relationship between body weight and depression. The aim was to determine if perception mediates the associations between measured weight and depression.
We analyzed the data of 13,548 adults age 18 or older, collected in the National Health and Nutrition Examination Survey, 2005-2008. Depression status was ascertained using the Patient Health Questionnaire; and the BMI was calculated from measured height and weight.
Among women, adjusting for perception weakened the relationship between measured weight and depression. The odds ratios (OR) of depression for being obese and overweight were 2.26 [95% confidence interval (1.50-3.40)] and 1.92 (1.29-2.85) before being adjusted for perception and 1.72 (1.01-2.92) and 1.62 (1.01-2.60) when perception was adjusted for. Independent from measured weight, women who perceived themselves as underweight [OR=2.95(1.47-5.14)] or overweight [1.73 (1.14-2.61)] had an increased odds of depression compared with women who perceived themselves as about the right weight. Among men, measured weight, neither overweight nor underweight, was associated with depression, perceiving oneself as underweight [OR=2.80 (1.42-5.54)] was associated with depression.
The inherent limitation of the study's cross-sectional design prevented the authors from investigating causality.
Perception may be more important than measured weight in the relationship with depression. Independent from measured weight either perceived under or overweight among women, or underweight among men, appear to be significantly associated with depression.
未能控制身体感知的混杂影响可能导致体重与抑郁之间关系的文献不一致。本研究旨在确定感知是否介导了测量体重与抑郁之间的关联。
我们分析了 2005-2008 年全国健康和营养调查中 13548 名年龄在 18 岁或以上的成年人的数据。使用患者健康问卷确定抑郁状况;并根据测量的身高和体重计算 BMI。
在女性中,调整感知后,测量体重与抑郁之间的关系减弱。调整感知前,肥胖和超重的抑郁比值比(OR)分别为 2.26(95%置信区间[1.50-3.40])和 1.92(1.29-2.85),调整感知后分别为 1.72(1.01-2.92)和 1.62(1.01-2.60)。独立于测量体重,感知自己体重过轻[OR=2.95(1.47-5.14)]或超重[1.73 (1.14-2.61)]的女性患抑郁的几率高于感知自己体重正常的女性。在男性中,超重或体重不足均与抑郁无关,而感知自己体重过轻[OR=2.80(1.42-5.54)]与抑郁相关。
研究的横断面设计固有局限性,使作者无法调查因果关系。
感知可能比测量体重更重要,与抑郁有关。独立于测量体重,女性感知自己体重过轻或超重,或男性感知自己体重过轻,似乎与抑郁显著相关。