FAPSE, University of Geneva, Switzerland.
Brain Lang. 2013 Aug;126(2):123-32. doi: 10.1016/j.bandl.2013.03.004. Epub 2013 May 23.
While the dynamics of lexical-semantic and lexical-phonological encoding in word production have been investigated in several event-related potential (ERP) studies, the estimated time course of phonological-phonetic encoding is the result of rather indirect evidence. We investigated the dynamics of phonological-phonetic encoding combining ERP analyses covering the entire encoding process in picture naming and word reading tasks by comparing ERP modulations in eight brain-damaged speakers presenting impaired phonological-phonetic encoding relative to 16 healthy controls. ERPs diverged between groups in terms of local waveform amplitude and global topography at ∼400 ms after stimulus onset in the picture naming task and at ∼320-350 ms in word reading and sustained until 100 ms before articulation onset. These divergences appeared in later time windows than those found in patients with underlying lexical-semantic and lexical-phonological impairment in previous studies, providing evidence that phonological-phonetic encoding is engaged around 400 ms in picture naming and around 330 ms in word reading.
虽然在几个事件相关电位（ERP）研究中已经研究了词汇语义和词汇语音编码的动态，但语音语音编码的估计时间过程是相当间接证据的结果。我们通过比较在图片命名和单词阅读任务中涵盖整个编码过程的 ERP 分析，结合对 8 位发音障碍者的 ERP 分析来研究语音语音编码的动态，这些发音障碍者相对于 16 位健康对照组表现出语音语音编码受损。在图片命名任务中，刺激后约 400 毫秒，在单词阅读和持续时间内，组间 ERP 在局部波形幅度和全局地形上存在差异，直到发音开始前 100 毫秒。这些差异出现在比以前研究中发现的有潜在词汇语义和词汇语音障碍的患者中更早的时间窗口中，这表明在图片命名中，语音语音编码大约在 400 毫秒左右，在单词阅读中大约在 330 毫秒左右。
