University of Maryland Greenebaum Cancer Center, Baltimore, MD 21201, USA.
Cancer J. 2013 May-Jun;19(3):222-30. doi: 10.1097/PPO.0b013e318293238d.
Over the last few decades, the integration of chemotherapy and radiation has played a crucial role in the management of locally advanced non-small cell lung cancer (NSCLC). Locally advanced NSCLC is a very heterogeneous disease. Because of this heterogeneity, advanced NSCLC can be managed in various ways depending on the bulk of disease, the comorbidities of the patient, and the expertise and resources of the treating physicians and facilities. This review describes the evolution of current treatment strategies and predicted future changes for the management of locally advanced NSCLC.
在过去几十年中，化疗和放疗的结合在局部晚期非小细胞肺癌（NSCLC）的治疗中发挥了关键作用。局部晚期 NSCLC 是一种非常异质性的疾病。由于这种异质性，根据疾病的严重程度、患者的合并症以及治疗医生和医疗机构的专业知识和资源，晚期 NSCLC 可以采用多种方式进行管理。本文综述了局部晚期 NSCLC 当前治疗策略的演变以及未来管理的预测变化。
