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对马蒂尼模型的看法。

Perspective on the Martini model.

机构信息

Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 7, 9747AG Groningen, The Netherlands.

出版信息

Chem Soc Rev. 2013 Aug 21;42(16):6801-22. doi: 10.1039/c3cs60093a.

Abstract

The Martini model, a coarse-grained force field for biomolecular simulations, has found a broad range of applications since its release a decade ago. Based on a building block principle, the model combines speed and versatility while maintaining chemical specificity. Here we review the current state of the model. We describe recent highlights as well as shortcomings, and our ideas on the further development of the model.

摘要

马蒂尼模型是一种用于生物分子模拟的粗粒度力场,自十年前发布以来,已经得到了广泛的应用。该模型基于积木原理,在保持化学特异性的同时,兼具速度和多功能性。在这里,我们回顾了该模型的现状。我们描述了最近的亮点和缺点,以及我们对模型进一步发展的想法。

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