Roche Phoebe, O'Neill Paul, Kavanagh Eoin, Rowley Helena
Department of Otolaryngology Head and Neck Surgery, Mater University Hospital, Dublin, Ireland.
BMJ Case Rep. 2013 May 23;2013:bcr2013008703. doi: 10.1136/bcr-2013-008703.
Lymphomas frequently occur as extranodal lesions in the head and neck, but are rarely seen in the palate. We present a case of isolated diffuse type B-cell lymphoma of the palate, which occurred in a 28-year-old man. The patient had no history of immune compromise, and he presented to the emergency department with a 7-month history of a painful, non-healing ulcerative mass in the hard and soft palate. Positron emission tomography facilitated pretreatment assessment of the extent and activity of the lesion. Histopathological and immunohistochemical analyses of biopsied tissue confirmed a diagnosis of diffuse type B-cell lymphoma. The clinical findings and therapeutic challenges in this heterogeneous group of malignancies are discussed.
淋巴瘤常作为头颈部的结外病变出现，但在腭部很少见。我们报告一例孤立性腭部弥漫性B细胞淋巴瘤病例，该病例发生在一名28岁男性身上。患者无免疫功能低下病史，因硬腭和软腭有一个疼痛、不愈合的溃疡性肿块7个月而就诊于急诊科。正电子发射断层扫描有助于对病变的范围和活性进行治疗前评估。活检组织的组织病理学和免疫组织化学分析证实为弥漫性B细胞淋巴瘤。本文讨论了这类异质性恶性肿瘤的临床发现和治疗挑战。
