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物质滥用治疗中公共卫生指标与处方阿片类药物滥用者注射处方阿片类药物之间的关联。

Associations between public health indicators and injecting prescription opioids by prescription opioid abusers in substance abuse treatment.

作者信息

Black Ryan A, Trudeau Kimberlee J, Cassidy Theresa A, Budman Simon H, Butler Stephen F

机构信息

Nova Southeastern University, Ft. Lauderdale, FL, USA.

出版信息

J Opioid Manag. 2013 Jan-Feb;9(1):5-17. doi: 10.5055/jom.2013.0142.

Abstract

OBJECTIVE

To determine what, if any, public health and societal impacts are associated specifically with injection of prescription opioids.

DESIGN

Cross-sectional observational study.

SETTING

Five hundred forty treatment facilities in 35 states across the United States performing Addiction Severity Index-Multimedia Version (ASI-MV) assessments.

PARTICIPANTS

Adult patients (29,459) who reported past 30-day abuse of any prescription opioid on the ASI-MV assessment between January 2007 and January 2011.

MAIN OUTCOME MEASURES

The public health indicators selected for this study were liver disease, HIV/AIDS status, recent visit to an emergency room, treatment for pain, treatment for overdosing, homelessness, residence with alcohol/substance abuser, and unemployment.

RESULTS

Prescription opioid injection was significantly associated with health problems, psychosocial problems, and utilization of medical services.

CONCLUSIONS

This study demonstrates an approach to measure the potential impact of injecting prescription opioids on public health indicators. Findings indicate a positive association between injection of prescription opioids and public health indicators suggesting a need for prescription opioid formulations that may inhibit injection of these medications.

摘要

目的

确定与注射处方阿片类药物具体相关的公共卫生和社会影响(若存在的话)。

设计

横断面观察性研究。

地点

美国35个州的540个治疗机构,这些机构进行成瘾严重程度指数 - 多媒体版(ASI - MV)评估。

参与者

2007年1月至2011年1月期间在ASI - MV评估中报告过去30天内滥用任何处方阿片类药物的成年患者(29459名)。

主要观察指标

本研究选择的公共卫生指标包括肝病、艾滋病毒/艾滋病状况、近期急诊就诊情况、疼痛治疗、过量用药治疗、无家可归、与酗酒/药物滥用者同住以及失业情况。

结果

注射处方阿片类药物与健康问题、心理社会问题以及医疗服务利用显著相关。

结论

本研究展示了一种衡量注射处方阿片类药物对公共卫生指标潜在影响的方法。研究结果表明,注射处方阿片类药物与公共卫生指标之间存在正相关,这表明需要有可抑制这些药物注射的处方阿片类药物剂型。

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