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眼内囊尾蚴病的临床和病理特征

Clinical and pathological characteristics of intraocular cysticercosis.

作者信息

Li Juan-Juan, Zhang Li-Wei, Li Hua, Hu Zhu-Lin

机构信息

Department of Ophthalmology, Red Cross Hospital of Yunnan, Kunming, China.

出版信息

Korean J Parasitol. 2013 Apr;51(2):223-9. doi: 10.3347/kjp.2013.51.2.223. Epub 2013 Apr 25.

Abstract

This study aimed to explore the clinical, radiological, and pathological characteristics of intraocular cysticercosis due to Taenia solium metacestode infection. Total 8 patients diagnosed with intraocular cysticercosis at the Red Cross Hospital of Yunnan Province, China were examined retrospectively. Patients with clear dioptic media had undergone fundus chromophotography. All patients underwent B ultrasonography of the ocular region (CT) successive scanning of the orbit and cerebral tissues. Parasites were extracted surgically and then examined pathologically. The fundus chromophotography showed a white and condensing scolex package in the vesicle. The B ultrasonic examination showed a vesicle-like echogenic mass in the vitreous chamber, in which the high-level echo spot was the cysticercus scolex. The pathological examinations showed that the vesicle wall exhibited hyaline degeneration, inflammatory cell infiltration, neuroglial fiber, and glial cell proliferation layers from the inside to the outside. The scolex is round and is composed of the outer tissue (the body wall) and the inner furrow tissue; these tissues migrated together. Primordially differentiated sucking discs were found in one case, but no hooklets were found. The inner scolex tissue was folded like a paper flower. The severity of intraocular disease is closely correlated with the pathophysiological processes of the cysticercus worm. Pathological examination of the intraocular lesions can help to evaluate the course of the disease as well as to provide a scientific basis for effective antiparasitic medication.

摘要

本研究旨在探讨猪带绦虫中绦期感染所致眼内囊尾蚴病的临床、影像学及病理特征。回顾性检查了在中国云南省红十字会医院确诊为眼内囊尾蚴病的8例患者。屈光介质清晰的患者接受了眼底彩色照相。所有患者均接受了眼部B超检查(CT)以及眼眶和脑组织的连续扫描。通过手术取出寄生虫,然后进行病理检查。眼底彩色照相显示囊泡内有白色致密的头节包块。B超检查显示玻璃体内有囊泡样回声团块,其中高回声点为囊尾蚴头节。病理检查显示,囊泡壁从内到外呈现透明变性、炎性细胞浸润、神经胶质纤维和胶质细胞增殖层。头节呈圆形,由外层组织(体壁)和内层沟组织组成;这些组织一起迁移。1例发现原始分化的吸盘,但未发现小钩。头节内部组织像纸花一样折叠。眼内疾病的严重程度与囊尾蚴的病理生理过程密切相关。眼内病变的病理检查有助于评估疾病进程,并为有效的抗寄生虫药物治疗提供科学依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee7/3662068/79589ff7b19d/kjp-51-223-g001.jpg

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