Department of Chemical Sciences, University of Naples Federico II, Naples, Italy.
Pigment Cell Melanoma Res. 2013 Sep;26(5):616-33. doi: 10.1111/pcmr.12121. Epub 2013 Jun 21.
Despite considerable advances in the past decade, melanin research still suffers from the lack of universally accepted and shared nomenclature, methodologies, and structural models. This paper stems from the joint efforts of chemists, biochemists, physicists, biologists, and physicians with recognized and consolidated expertise in the field of melanins and melanogenesis, who critically reviewed and experimentally revisited methods, standards, and protocols to provide for the first time a consensus set of recommended procedures to be adopted and shared by researchers involved in pigment cell research. The aim of the paper was to define an unprecedented frame of reference built on cutting-edge knowledge and state-of-the-art methodology, to enable reliable comparison of results among laboratories and new progress in the field based on standardized methods and shared information.
尽管在过去十年中取得了相当大的进展，但黑色素研究仍然缺乏普遍接受和共享的命名法、方法和结构模型。本文源于化学家、生物化学家、物理学家、生物学家和医生的共同努力，他们在黑色素和黑色素生成领域具有公认的和巩固的专业知识，他们对方法、标准和协议进行了批判性审查和实验性重新评估，首次为参与色素细胞研究的研究人员提供了一套一致推荐的程序，以采用和共享。本文的目的是定义一个前所未有的参考框架，建立在最先进的知识和最先进的方法的基础上，使实验室之间的结果能够可靠地进行比较，并基于标准化方法和共享信息在该领域取得新的进展。
