Greenspan J S, Wolfson M R, Holt W J, Shaffer T H
Newborn Service, Temple University Hospital, Philadelphia, PA 19140.
Pediatr Pulmonol. 1990;8(4):254-8. doi: 10.1002/ppul.1950080408.
The acute effects of nasogastric (NG) and orogastric (OG) tube placement on pulmonary function of neonates was assessed as a function of infant weight. Lung function was obtained on 14 healthy infants weighing less than 2 kg and 10 infants heavier than 2 kg with an NG and an OG tube in place. Additionally, 15 infants were studied for a third time without gastric intubation. Lung function was determined with an esophageal balloon and by pneumotachography (PeDS) via the least mean square analysis technique. Neither the below-2 kg infants nor the above-2 kg infants had apparent clinical compromise with NG and OG tube placement. Infants weighing less than 2 kg, however, demonstrated diminished minute ventilation and respiratory rate and had increased pulmonary resistance, resistive work of breathing, and peak transpulmonary pressure change with NG tube, as compared to OG tube, placement. The above-2 kg infants demonstrated no change in pulmonary function with NG vs. OG tube placement. These data indicate that small neonates demonstrate significant pulmonary compromise with NG placement that may not be clinically apparent.
评估鼻胃管（NG）和口胃管（OG）放置对新生儿肺功能的急性影响，并将其作为婴儿体重的函数进行研究。对14名体重小于2千克的健康婴儿和10名体重大于2千克的婴儿在放置NG管和OG管的情况下进行肺功能检测。此外，对15名婴儿在未进行胃插管的情况下进行了第三次研究。通过食管气囊和采用最小均方分析技术的呼吸流速描记法（PeDS）来测定肺功能。体重小于2千克的婴儿和体重大于2千克的婴儿在放置NG管和OG管时均未出现明显的临床不良反应。然而，与放置OG管相比，体重小于2千克的婴儿在放置NG管时表现出分钟通气量和呼吸频率降低，肺阻力、呼吸阻力功以及经肺峰值压力变化增加。体重大于2千克的婴儿在放置NG管和OG管时肺功能未出现变化。这些数据表明，小体重新生儿在放置NG管时会出现明显的肺功能损害，而这在临床上可能并不明显。
