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波兰新生儿重症监护病房分离的大肠杆菌的分子流行病学、质粒分析、毒力和耐药性。

Molecular epidemiology, plasmid analysis, virulence, and resistance of Escherichia coli isolated from neonatal intensive care units in Poland.

机构信息

Jagiellonian University Medical College, 31-121 Krakow, Poland.

出版信息

Diagn Microbiol Infect Dis. 2013 Aug;76(4):542-5. doi: 10.1016/j.diagmicrobio.2013.04.016. Epub 2013 May 24.

Abstract

We investigated the set of Escherichia coli isolates originating from newborns in relation to resistance, virulence factors (VFs), phylogenetic groups, plasmid replicon typing, and genotypes. The most isolates were clustered in ECOR group B2. Extended-spectrum beta-lactamase phenotype was found in 27.7% of isolates. The ST131 clone was detected among 33 strains, 12 of which carried the CTX-M-15 gene. Most VFs were detected among ST131 isolates and in the B2 group. IbeA gene was found more frequently in the blood isolates, while the iha gene, in the urine isolates. The 3 most prevalent replicon types were IncFIB, IncF, and IncFIA.

摘要

我们研究了源自新生儿的一组大肠杆菌分离株,涉及耐药性、毒力因子(VF)、系统发育群、质粒复制子分型和基因型。大多数分离株聚集在 ECOR 组 B2 中。27.7%的分离株表现出广谱β-内酰胺酶表型。在 33 株菌株中检测到 ST131 克隆,其中 12 株携带 CTX-M-15 基因。大多数 VF 存在于 ST131 分离株和 B2 组中。IbeA 基因在血液分离株中更为常见,而 iha 基因在尿液分离株中更为常见。最常见的 3 种复制子类型是 IncFIB、IncF 和 IncFIA。

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