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采用低能量飞秒激光的椭圆薄瓣 LASIK 的临床安全性和有效性。

Clinical safety and efficacy of elliptical thin-flap LASIK using a low-pulse energy femtosecond laser.

机构信息

Universal Eye Center, Zhong-Li, Taoyüan City, 320066, Taiwan (R.O.C.).

Universal Eye Center, Long-Tan, No. 483, Yanping Rd., Zhongli Dist., Taoyüan City, 320066, Taiwan (R.O.C.).

出版信息

Sci Rep. 2024 Oct 19;14(1):24563. doi: 10.1038/s41598-024-76215-1.

DOI:10.1038/s41598-024-76215-1
PMID:39427010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11490556/
Abstract

This study assessed the clinical safety and efficacy of elliptical thin-flap LASIK with a low-pulse energy femtosecond laser in 3 thickness subgroups (85, 90, and 100 μm). A total of 80 patients who underwent bilateral LASIK surgery at Taiwan between April and September 2019 were retrospectively enrolled. Elliptical corneal flaps with wide temporal hinges and inverted-angled side cuts were created. Target flap thickness was calculated on the basis of residual stromal bed thickness and percent tissue altered. Before flap creation, an optical coherence tomography image for visualization of the precut flap position was obtained with the built-in camera. At postoperative month 1, the overall mean logMAR uncorrected distance visual acuity (UDVA) was - 0.04 ± 0.07 (20/18 Snellen), with 96% of eyes achieving UDVA of 20/20 or better. Postoperative mean manifest spherical equivalent was - 0.37 ± 0.42 D at 1 month. The visual and refractive outcomes in each of the 3 subgroups were similar. The achieved flap thicknesses were found to be highly predictable and consistent in the respective thickness subgroups. Optical coherence tomography-guided thin-flap LASIK performed with the low-pulse energy femtosecond laser was found to be safe with no intraoperative or postoperative complications.

摘要

本研究评估了低能量飞秒激光在 3 个厚度亚组(85、90 和 100μm)下的椭圆薄瓣 LASIK 的临床安全性和疗效。2019 年 4 月至 9 月期间,共有 80 名在台湾接受双侧 LASIK 手术的患者被回顾性纳入研究。采用宽颞侧铰链和反向角度侧切口制作椭圆形角膜瓣。目标瓣厚度根据剩余基质床厚度和组织改变百分比计算。在制作瓣之前,使用内置相机获得用于可视化预切割瓣位置的光学相干断层扫描图像。术后 1 个月,总体平均 logMAR 未矫正距离视力(UDVA)为-0.04±0.07(20/18 Snellen),96%的眼睛达到 20/20 或更好的 UDVA。术后 1 个月平均等效球镜为-0.37±0.42 D。3 个亚组的视觉和屈光结果相似。在各自的厚度亚组中,发现所获得的瓣厚度具有高度可预测性和一致性。使用低能量飞秒激光进行的 OCT 引导的薄瓣 LASIK 是安全的,没有术中或术后并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/4f4742b2a8fd/41598_2024_76215_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/bc4f3394aad5/41598_2024_76215_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/517f660baf53/41598_2024_76215_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/1d92921341e5/41598_2024_76215_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/8e3cff1c5054/41598_2024_76215_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/b08d600ea66d/41598_2024_76215_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/4f4742b2a8fd/41598_2024_76215_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/bc4f3394aad5/41598_2024_76215_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/517f660baf53/41598_2024_76215_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/1d92921341e5/41598_2024_76215_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/8e3cff1c5054/41598_2024_76215_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/b08d600ea66d/41598_2024_76215_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2da8/11490556/4f4742b2a8fd/41598_2024_76215_Fig6_HTML.jpg

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本文引用的文献

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J Ophthalmic Vis Res. 2023 Feb 21;18(1):3-14. doi: 10.18502/jovr.v18i1.12720. eCollection 2023 Jan-Mar.
2
Elliptical versus circular flap configuration in myopic eyes undergoing femtosecond laser keratomileusis surgery: A contralateral eye study.在接受飞秒激光角膜磨镶术的近视眼中,椭圆形与圆形角膜瓣构型:一项对侧眼研究。
Indian J Ophthalmol. 2021 Dec;69(12):3457-3462. doi: 10.4103/ijo.IJO_836_21.
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Thin-Flap Laser In Situ Keratomileusis-Associated Dry Eye: A Comparative Study Between Femtosecond Laser and Mechanical Microkeratome-Assisted Laser In Situ Keratomileusis.
薄瓣准分子原位角膜磨镶术相关干眼:飞秒激光与机械微型角膜刀辅助准分子原位角膜磨镶术的比较研究
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Comparison of clinical outcomes after femtosecond laser keratomileusis in eyes with low or high myopia.低近视或高度近视患者飞秒激光角膜磨镶术后临床结果的比较。
Int J Ophthalmol. 2020 Nov 18;13(11):1780-1787. doi: 10.18240/ijo.2020.11.15. eCollection 2020.
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Eighty-micron flap femtosecond-assisted LASIK for the correction of myopia and myopic astigmatism.80 微米瓣飞秒辅助 LASIK 治疗近视及近视散光。
J Cataract Refract Surg. 2021 Apr 1;47(4):445-449. doi: 10.1097/j.jcrs.0000000000000484.
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Managements of vertical gas breakthrough in femtosecond laser assisted LASIK.飞秒激光辅助准分子原位角膜磨镶术中垂直性气体突破的处理
Int J Ophthalmol. 2020 Sep 18;13(9):1503-1504. doi: 10.18240/ijo.2020.09.25. eCollection 2020.
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