结直肠癌新出现症状的评估：与性格、人口统计学和肿瘤特征的关联。
Appraisal of emerging symptoms of colorectal cancer: associations with dispositional, demographic, and tumor characteristics.
作者信息
Ristvedt Stephen L, Pruitt Sandi L, Trinkaus Kathryn M
机构信息
Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave., Campus Box 8134, St. Louis, MO, 63110, USA,
出版信息
J Behav Med. 2014 Aug;37(4):698-708. doi: 10.1007/s10865-013-9519-4. Epub 2013 May 28.
The time it takes for individuals to realize that their emerging colorectal cancer (CRC) symptoms are serious is often an impediment to expeditious help-seeking. Tailored educational efforts to hasten symptom appraisal time would benefit from knowledge of the characteristics of individuals who tend to neglect their symptoms as well as the nature of symptoms that are most often neglected. In a sample of 112 CRC patients, we investigated associations between duration of symptom appraisal and: (1) trait anxiety, and (2) tumor location, which affects symptomatology. Symptom appraisal duration was associated with a sex-by-anxiety interaction (p = 0.007). The longest times (in weeks) were among high anxiety females (Mdn = 26.0) and low anxiety males (Mdn = 17.0), with shorter times among low anxiety females (Mdn = 9.0) and high anxiety males (Mdn = 2.0). Symptom appraisal times were also longer for patients with distal (vs. proximal) tumors (p = 0.036).
个体意识到其新发结直肠癌（CRC）症状严重所需的时间，往往会阻碍他们迅速寻求帮助。了解那些往往忽视自身症状的个体特征以及最常被忽视的症状性质，将有助于开展针对性的教育工作，以缩短症状评估时间。在112名CRC患者样本中，我们研究了症状评估持续时间与以下因素之间的关联：（1）特质焦虑，以及（2）影响症状表现的肿瘤位置。症状评估持续时间与性别-焦虑交互作用相关（p = 0.007）。最长的时间（以周为单位）出现在高焦虑女性（中位数 = 26.0）和低焦虑男性（中位数 = 17.0）中，而低焦虑女性（中位数 = 9.0）和高焦虑男性（中位数 = 2.0）的时间较短。远端（相对于近端）肿瘤患者的症状评估时间也更长（p = 0.036）。
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