Meyer Sascha, Willhelm Christiane, Girisch Wolfgang, Gottschling Sven, Gräber Stefan, Gortner Ludwig
University of Saarland, Medical School, University Children's Hospital of Saarland, Department of Paediatrics and Neonatology, Building 9, 66421 Homburg, Germany.
World Health Popul. 2013;14(2):24-32. doi: 10.12927/whp.2013.23272.
There is a lack of up-to-date, systematic reviews that critically assess the role and potential limitations of evidence-based medicine and systematic Cochrane reviews originating in developing countries.
We performed a systematic literature review of all Cochrane reviews published between 1997 and 2010 by the Cochrane Neonatal Review Group (CNRG) in the field of neuropediatrics. The main outcome parameter of our review was the assessment of the percentage of reviews that originated in developing countries and the number of reviews that provided conclusive/ inconclusive data.
In total, 262 reviews were performed in the field of neonatology and 112 in the field of neuropediatrics. Only a small fraction (15/262 in neonatology [7/15 conclusive] and 16/112 in neuropediatrics [9/16 conclusive]) originated in developing countries.
There is an ongoing need for high-quality research that addresses specific issues that are most relevant to the medical care of children in developing countries. Funding and research agencies will play a pivotal role in selecting the most appropriate research programs for the developing world.
目前缺乏对循证医学的作用及潜在局限性进行批判性评估的最新系统性综述，以及源自发展中国家的Cochrane系统评价。
我们对Cochrane新生儿综述小组（CNRG）在1997年至2010年间发表的神经儿科学领域的所有Cochrane综述进行了系统性文献回顾。我们综述的主要结果参数是评估源自发展中国家的综述所占百分比以及提供确定性/非确定性数据的综述数量。
新生儿学领域共进行了262项综述，神经儿科学领域进行了112项综述。只有一小部分（新生儿学领域为15/262 [7/15为确定性]，神经儿科学领域为16/112 [9/16为确定性]）源自发展中国家。
持续需要开展高质量研究，以解决与发展中国家儿童医疗保健最相关的特定问题。资助机构和研究机构在为发展中世界选择最合适的研究项目方面将发挥关键作用。
