Zuo Ai-Xue, Li Li, Ma Yun-Shu, Rao Gao-Xiong
College of Pharmacy, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China.
Zhongguo Zhong Yao Za Zhi. 2013 Feb;38(4):574-7.
Eight alkaloids were isolated from the thin sulfuric acid extracts of the fresh roots of Stephania dentifolia by aluminum oxide, silica and Sephadex LH-20 column chromatography methods. Based on the spectroscopic analysis and chemical evidence, the structures of these alkaloids were identified as sinoacutine (1), sinomenine (2), cephamonine (3), tetrahydropalmatine (4), capaurine (5), stepharanine (6), (+)-stepharine (7) and palmatine (8). All compounds were obtained from this plant for the first time.
采用氧化铝、硅胶和葡聚糖凝胶LH - 20柱色谱法，从齿叶千金藤新鲜根的稀硫酸提取物中分离得到8种生物碱。基于光谱分析和化学证据，确定这些生物碱的结构分别为华千金藤碱（1）、青藤碱（2）、头花千金藤碱（3）、四氢巴马汀（4）、紫堇球碱（5）、千金藤宁碱（6）、（+）-千金藤碱（7）和巴马汀（8）。所有化合物均首次从该植物中获得。
