The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, P.R. China.
Nat Prod Res. 2010 Aug;24(13):1243-7. doi: 10.1080/14786410903125393.
Further investigation on the phytochemistry of the medicinal plant Stephania viridiflavens led to the isolation of a new naturally occurring aporphine alkaloid, (+)-6R, 6aS-isocorydine N(beta)-oxide (1), together with three known aporphine alkaloids: (+)-6R, 6aS-corydine N(beta)-oxide (2), (+)-N-methyl-laurotetanine (3) and (+)-stepharine (4). The structure and stereochemistry of 1 were determined on the basis of spectroscopic methods and confirmed by synthesis. Alkaloids 2-4 were isolated for the first time from this species.
进一步研究药用植物Stephania viridiflavens 的植物化学，从中分离得到一个新的天然阿朴啡类生物碱：（+）-6R,6aS-异紫堇林碱 N-β-氧化物（1），以及三个已知的阿朴啡类生物碱：（+）-6R,6aS-紫堇林碱 N-β-氧化物（2）、（+）-N-甲基劳丹碱（3）和（+）-石蚕属碱（4）。根据光谱方法确定了 1 的结构和立体化学，并通过合成得到了证实。生物碱 2-4 是首次从该种植物中分离得到的。
