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单次坐骨棘皮质类固醇注射治疗持续性妊娠相关骨盆痛女性的功能改善:一项随机双盲对照试验。

Improved function in women with persistent pregnancy-related pelvic pain after a single corticosteroid injection to the ischiadic spine: a randomized double-blind controlled trial.

机构信息

Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine Unit, Uppsala University, Uppsala, Sweden.

出版信息

Physiother Theory Pract. 2013 Jul;29(5):371-8. doi: 10.3109/09593985.2012.734009.

Abstract

BACKGROUND

Pregnancy-related low back and pelvic pain is a worldwide problem. A large proportion of women still experience disabling daily back pain 2 years after childbirth, resulting in major changes in activities and general well-being. In spite of this, the source of pain and effective treatment are uncertain.

OBJECTIVE

To evaluate the short-term effects on function of a single corticosteroid injection treatment to the ischiadic spine in women with persistent pregnancy-related pelvic pain (PPPP).

METHODS

Thirty-six women were allocated to injection treatment with slow-release triamcinolone and lidocain or saline and lidocain, given once at the sacrospinous ligament insertion on the ischiadic spine bilaterally with follow-up at 4 weeks. Outcome measures were Disability Rating Index (DRI), self-rated functional health (SF-36), gait speed and endurance (6MWT), and strength and endurance of trunk muscles (isometric trunk extensor and flexor tests).

RESULTS

Women in the triamcinolone group showed significantly improved DRI (p  =  0.046), 6MWT (p  =  0.016), and isometric trunk extensor tests (p  =  0.004), as compared with the saline group. Close co-variation was shown between improved function and reduced pain intensity.

CONCLUSIONS

Improved function was achieved among women with PPPP after a single injection treatment with slow-release corticosteroid. The effect was positively correlated to the reduced pain intensity.

摘要

背景

与妊娠相关的腰背和骨盆疼痛是一个全球性问题。很大一部分女性在分娩后 2 年仍会经历致残性的腰背疼痛,导致活动和整体健康状况发生重大变化。尽管如此,疼痛的根源和有效的治疗方法仍不确定。

目的

评估单次坐骨棘皮质类固醇注射治疗持续性妊娠相关骨盆疼痛(PPPP)女性功能的短期效果。

方法

36 名女性被分配到接受双侧坐骨棘骶棘韧带附着处缓慢释放曲安奈德和利多卡因或生理盐水和利多卡因注射治疗,在 4 周时进行随访。结局指标为残疾评定指数(DRI)、自我评定的功能健康(SF-36)、步态速度和耐力(6MWT)以及躯干肌肉的力量和耐力(等长躯干伸肌和屈肌测试)。

结果

与生理盐水组相比,曲安奈德组的 DRI(p  =  0.046)、6MWT(p  =  0.016)和等长躯干伸肌测试(p  =  0.004)显著改善。功能改善与疼痛强度降低呈密切的共变关系。

结论

在接受缓慢释放皮质类固醇单次注射治疗后,PPPP 女性的功能得到改善。这种效果与疼痛强度的降低呈正相关。

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