Suppr超能文献

坐骨棘注射皮质类固醇治疗妊娠后出现的长期骶骨下腰痛的女性疼痛:一项随机、双盲、对照试验。

Corticosteroid injection treatment to the ischiadic spine reduced pain in women with long-lasting sacral low back pain with onset during pregnancy: a randomized, double blind, controlled trial.

机构信息

Department of Physiotherapy, Sundsvall Hospital, Sundsvall, Sweden.

出版信息

Spine (Phila Pa 1976). 2009 Oct 1;34(21):2254-8. doi: 10.1097/BRS.0b013e3181b07eac.

Abstract

STUDY DESIGN

Randomized double blind controlled clinical trial.

OBJECTIVE

To evaluate the pain relief effect of locally injected corticosteroid treatment in women with long-lasting sacral low back pain with onset during pregnancy.

SUMMARY OF BACKGROUND DATA

Pregnancy-related low back pain is a global problem. Almost 1 of 10 women still experienced disabling daily back pain 2 years after childbirth with high impact on the individual, family, and society. On spite of this, the sources of pain and effective treatment are uncertain.

METHODS

Thirty-six women were allocated to injection treatment, with slow-release triamcinolone and lidocaine or saline and lidocaine, given at the sacrospinous ligament insertion on the ischiadic spine bilaterally with 4 weeks follow-up time. Primary outcome measure was reported pain intensity on visual analogue scale and secondary outcome measures number of pain-drawing locations and pain-provoking test results. RESULTS.: The triamcinolone treatment group had significantly reduced pain intensity, number of pain locations, and pain-provoking test results between baseline and follow-up as compared with the saline treatment group. The absolute median change of visual analogue scale score in the triamcinolone treatment group was -24 mm and in the saline group +4.5 mm (P < 0.05). A reduced number of pain drawing locations was reported by 16 of 18 women in the triamcinolone group as compared with 10 of 18 in the saline group (P < 0.05). In the triamcinolone treatment group, 17 of 18 women had an improved pain provocation test result as compared with 9 of 18 in the saline treatment group (P < 0.01).

CONCLUSION

The anatomic region around the sacrospinous ligament insertion on the ischial spine is suggested to be one source of long-lasting sacral low back pain with onset during pregnancy. The pain was relieved by slow-release corticosteroid injection treatment to the ischial spine.

摘要

研究设计

随机双盲对照临床试验。

目的

评估局部注射皮质类固醇治疗妊娠后发生的持续性骶骨下腰痛的止痛效果。

背景资料总结

妊娠相关腰痛是一个全球性问题。几乎每 10 名女性中就有 1 名在分娩后 2 年内仍经历着使日常活动受限的腰痛,这对个人、家庭和社会都有很大的影响。尽管如此,疼痛的来源和有效的治疗方法仍不确定。

方法

36 名女性被分配到注射治疗组,在双侧坐骨棘突上的骶棘韧带附着处注射缓慢释放的曲安奈德和利多卡因或生理盐水和利多卡因,并在 4 周的随访时间内进行治疗。主要观察指标为视觉模拟评分法报告的疼痛强度,次要观察指标为疼痛绘图部位的数量和疼痛诱发试验结果。

结果

与生理盐水治疗组相比,曲安奈德治疗组在基线和随访时的疼痛强度、疼痛部位数量和疼痛诱发试验结果均显著降低。曲安奈德治疗组的视觉模拟评分法评分绝对中位数变化为-24mm,生理盐水组为+4.5mm(P<0.05)。18 名曲安奈德组中有 16 名女性报告疼痛绘图部位数量减少,而生理盐水组中有 10 名(P<0.05)。在曲安奈德治疗组中,18 名女性中有 17 名的疼痛诱发试验结果得到改善,而生理盐水治疗组中只有 9 名(P<0.01)。

结论

建议坐骨棘突上的骶棘韧带附着处周围的解剖区域是妊娠后发生的持续性骶骨下腰痛的一个来源。通过向坐骨棘注射缓慢释放的皮质类固醇,可以缓解疼痛。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验