基于噻吩的新型甲基丙烯酸酯和苯乙烯单体的共聚物：合成、表征、单体反应比、热性能和生物活性。

Copolymers of novel methacrylic and styrenic monomer based on the thiophene: synthesis, characterization, monomer reactivity ratios, thermal properties, and biological activity.

机构信息

Department of Chemistry, Faculty of Science and Arts, University of Afyon Kocatepe, Afyonkarahisar, Turkey.

出版信息

J Biomater Sci Polym Ed. 2013;24(10):1198-218. doi: 10.1080/09205063.2012.745715. Epub 2012 Nov 26.

DOI:10.1080/09205063.2012.745715

Abstract

The free radical copolymerization of 2-thienylmethyl 4-vinylbenzyl ether (TMVBE) with 2-oxo-2-(2-thienylmethoxy)ethyl-2-methylacrylate (TMOEM) has been carried out in 1,4-dioxane at 65 °C ± 1 and were analyzed by Fourier transform infrared, (1)H NMR, and (13)C NMR spectroscopy. (1)H NMR analysis was used to determine the molar fractions of TMVBE and TMOEM in the copolymers. The monomer reactivity ratios were calculated according to the general copolymerization equation using Kelen-Tüdõs and Finemann-Ross linearization methods. The reactivity ratios indicated a tendency toward alternation copolymerization. The thermal behaviors of copolymers with various compositions were investigated by differential scanning calorimetry and thermogravimetric analysis. Also, the apparent thermal decomposition activation energies were calculated by the Ozawa and Kissinger methods with a Shimadzu TGA 60 thermogravimetric analysis thermobalance. All the products showed moderate activity against different strains of bacteria and fungi.

摘要

2-噻吩甲基 4-乙烯基苄基醚（TMVBE）与 2-氧代-2-（2-噻吩甲氧基）乙基-2-甲基丙烯酸酯（TMOEM）在 1,4-二氧六环中于 65°C±1 下进行自由基共聚，并通过傅里叶变换红外光谱、（1）H NMR 和（13）C NMR 光谱进行分析。（1）H NMR 分析用于确定共聚物中 TMVBE 和 TMOEM 的摩尔分数。根据一般共聚方程，使用 Kelen-Tüdõs 和 Finemann-Ross 线性化方法计算单体的反应性比。反应性比表明交替共聚的趋势。通过差示扫描量热法和热重分析研究了具有不同组成的共聚物的热行为。此外，通过 Ozawa 和 Kissinger 方法以及 Shimadzu TGA 60 热重分析热天平计算了表观热分解活化能。所有产物对不同菌株的细菌和真菌均表现出中等的活性。