Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, DE-70569 Stuttgart, Germany.
Org Lett. 2013 Jun 7;15(11):2858-61. doi: 10.1021/ol401185t. Epub 2013 May 28.
The chemoselective reduction of alkyne, ketones, or nitro groups using (Ph3P)3RuCl2 as an inexpensive catalyst and Zn/water as a stoichiometric reductant is reported. Depending on the nature of the additive and the temperature, good chemoselectivities were observed allowing, e.g., for the selective reduction of a nitro group in the presence of a ketone or an alkyne.
本文报道了使用(Ph3P)3RuCl2作为廉价催化剂和 Zn/水作为化学计量还原剂，对炔烃、酮或硝基进行化学选择性还原的方法。根据添加剂的性质和温度的不同，可以观察到良好的化学选择性，例如，可以在酮或炔烃存在的情况下选择性还原硝基。
