Li Lu-xi, Liu Wei, Ji Jian
Tianjin Medical University Eye Hospital, Tianjin, China.
Zhonghua Yan Ke Za Zhi. 2013 Feb;49(2):185-8.
Glaucoma is an eye disease that can lead to irreversible visual impairment. Trabeculectomy remains the most common operation for glaucoma therapy. The formation of functional filtering bleb is the key to the success of surgery. But many studies have found that anti-glaucoma surgeries affected the normal function of the tear film, which can cause the change of the structure of ocular surface resulting in an uncomfortable feeling and dry eye. Most investigators have suggested that the alteration of ocular surface by trabeculectomy is due partially to the damage of ocular surface tissues and topical application of the drugs of anti-metabolism as well as the lack of vascular supply of ultra-thin post-operative filtering bleb.
青光眼是一种可导致不可逆视力损害的眼部疾病。小梁切除术仍然是青光眼治疗最常见的手术方式。功能性滤过泡的形成是手术成功的关键。但许多研究发现,抗青光眼手术会影响泪膜的正常功能,这可能导致眼表结构改变,从而产生不适感和干眼。大多数研究者认为,小梁切除术导致的眼表改变部分归因于眼表组织的损伤、抗代谢药物的局部应用以及术后超薄滤过泡缺乏血管供应。