Donner C, Simon P, Gosselin F, Vermeylen D, Avni F, Liesnard C, Vamos E, Cochaux P, Vassart G, Rodesch F
Laboratoire de Cytogénétique, Hôpital Universitaire Brugmann.
Rev Med Brux. 1990 Jun;11(6):217-22.
The first diagnostic cordocentesis was performed in our unit in october 1985. Our 4-year experience is reported: 391 cordocentesis were performed in 360 patients during gestational weeks 14 to 42. The first attempt was successful in 90% of the procedures, 4 samplings failed, there were 4 fetal deaths within one week after diagnostic cordocentesis, one of them appears to be directly linked to the punction. A transient fetal bradycardia was observed in 9.9% of the cases, bleeding occurred in 19% of the cases. The indications for cordocentesis were: risk of fetal infection, karyotyping, hemopathy, search for paternity, assessment of fetal acid-base status, biochemical dosage. Our data confirm that cordocentesis is a safe and reliable diagnostic procedure providing guidelines for management of the pregnancy.
1985年10月，我们科室进行了首例诊断性脐带穿刺术。现将我们4年的经验报告如下：在妊娠14至42周期间，对360例患者进行了391次脐带穿刺术。首次穿刺成功率为90%，4次采样失败，诊断性脐带穿刺术后1周内有4例胎儿死亡，其中1例似乎与穿刺直接相关。9.9%的病例观察到短暂性胎儿心动过缓，19%的病例发生出血。脐带穿刺术的适应证包括：胎儿感染风险、染色体核型分析、血液病、亲子鉴定、评估胎儿酸碱状态、生化检测。我们的数据证实，脐带穿刺术是一种安全可靠的诊断方法，可为妊娠管理提供指导。
