Donner C, Simon P, Avni F, Jauniaux E, Rodesch F
Department of Obstetrics & Gynecology, Hopital Erasme, Free University of Brussels, Belgium.
Eur J Obstet Gynecol Reprod Biol. 1989 May;31(2):119-25. doi: 10.1016/0028-2243(89)90172-x.
The first diagnostic cordocentesis was performed in our unit in October 1985, our 2-year experience is reported. 144 samplings were performed in 137 patients (139 fetuses - 2 patients had twin pregnancies) during gestational weeks 14 to 42. The first attempt was successful in 80% of the procedures, 4 samplings failed. There were no fetal deaths within 3 days after diagnostic cordocentesis, a transient fetal bradycardia was observed in 12.2% of the cases, bleeding occurred in 13.6% of the cases. The indications for cordocentesis were: risk of fetal infection, karyotyping, hemophilia A, alloimmunisation, search for paternity, assessment of fetal acid-base status. Our data confirm that cordocentesis is a safe and reliable diagnostic procedure providing guidelines for management of the pregnancy.
1985年10月我们科室进行了首例诊断性脐带穿刺术，现报告我们2年的经验。在妊娠14至42周期间，对137例患者（139例胎儿——2例患者为双胎妊娠）进行了144次采样。首次尝试在80%的操作中成功，4次采样失败。诊断性脐带穿刺术后3天内无胎儿死亡，12.2%的病例观察到短暂性胎儿心动过缓，13.6%的病例发生出血。脐带穿刺术的适应证为：胎儿感染风险、染色体核型分析、甲型血友病、同种免疫、亲子鉴定、评估胎儿酸碱状态。我们的数据证实，脐带穿刺术是一种安全可靠的诊断方法，可为妊娠管理提供指导。
