Shen Pei, Zhang ShanYong, Yang Chi, Liu XiuMing, Wei KuiJie, Wang LiZhen, Wang XiaoYue, Haddad Majd S
Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, People's Republic of China.
J Craniofac Surg. 2013 May;24(3):748-52. doi: 10.1097/SCS.0b013e318285d96e.
The aim of this study was to examine the changes of the synovial tissue in rabbit temporomandibular joint (TMJ) internal derangement (ID) models using light and electron microscope. Thirteen rabbits were included in our study. The right TMJ of all animals were used as the experimental group while the left ones as the control group. ID model was established by using elastic rubber rope to stretch anteriorly. Synovial tissues were collected and examined by light and electron microscope to observe microstructure and ultrastructure changes after establishing the model. CD34 was used to count small blood vessels. A paired t test was performed with SPSS 16.0 software package to compare the data of the experimental and the control side. The average number of small blood vessels in the experimental side was significantly greater than the control side both in the first and second week. Numerous synovial cells of type A and type B were detected under electron microscope, and type A cells shrunk after a period of time. This study is helpful to understand the development of the TMJ intra-articular adhesion.
本研究旨在利用光学显微镜和电子显微镜观察兔颞下颌关节（TMJ）内紊乱（ID）模型中滑膜组织的变化。本研究纳入了13只兔子。所有动物的右侧TMJ作为实验组，左侧作为对照组。通过使用弹性橡胶绳向前拉伸建立ID模型。收集滑膜组织，用光学显微镜和电子显微镜观察建模后微观结构和超微结构的变化。用CD34计数小血管。使用SPSS 16.0软件包进行配对t检验，以比较实验组和对照组的数据。在第一周和第二周，实验组小血管的平均数量均显著多于对照组。电子显微镜下检测到大量A型和B型滑膜细胞，一段时间后A型细胞萎缩。本研究有助于了解TMJ关节内粘连的发展。
