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[大学眼库新卫生和技术规则前后供体角膜质量及死亡与保存间隔时间的比较分析]

[Comparative analysis of the donor cornea quality and of the interval between death and preservation before and after new sanitary and technique rules in a University Eye Bank].

作者信息

Zantut Fabio, Holzchuh Ricardo, Boni Reginaldo Carlos, Mackus Eva Cristina, Zantut Paulo Roberto, Nakano Claudio, Netto Adamo Lui, Hida Richard Yudi

机构信息

Setor de Catarata, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil.

出版信息

Arq Bras Oftalmol. 2012 Nov-Dec;75(6):398-401. doi: 10.1590/s0004-27492012000600005.

Abstract

PURPOSE

To compare the interval between death and enucleation (ΔT-O-E), between enucleation and preservation (ΔT-E-P) and the quality of the cornea before and after the implantation of new technique and sanitary rules.

METHODS

A retrospective study that evaluated the records of cornea donors in Sao Paulo's Santa Casa Eye Tissue Bank 2 years before and 2 years after the implementation new sanitary rules.

RESULTS

An increase was observed in the absolute number of 205 to 374 donors following the adopted changes. There was no statistically significant difference in Δt-O-E and ΔT-E-P before and after the implemented changes. Of the total of 1,105 donor corneas, 388 donor corneas were observed before the changes and 717 donor corneas after the implemented changes. We observed a statistically significant increase in grading of donor cornea quality from 1.76 ± 0.90 to 1.94 ± 0.88 after the implementation of new standards of resolution.

CONCLUSION

After the changes required by Resolution 347, there was a large increase in the number of donated, taken and preserved corneas. The BTO has not diminished the ΔT O-E and ΔT E-P. Cornea quality presented itself lower after the new rules.

摘要

目的

比较新技术和卫生规则实施前后死亡与眼球摘除之间的时间间隔(ΔT-O-E)、眼球摘除与保存之间的时间间隔(ΔT-E-P)以及角膜质量。

方法

一项回顾性研究,评估圣保罗圣卡塔琳娜眼组织库在新卫生规则实施前两年和实施后两年的角膜捐赠者记录。

结果

采用这些改变后,捐赠者的绝对数量从205人增加到374人。实施这些改变前后,Δt-O-E和ΔT-E-P在统计学上没有显著差异。在总共1105个捐赠角膜中,改变前观察到388个捐赠角膜,实施改变后观察到717个捐赠角膜。实施新的分辨率标准后,我们观察到捐赠角膜质量分级从1.76±0.90显著提高到1.94±0.88。

结论

在第347号决议要求的改变之后,捐赠、摘取和保存的角膜数量大幅增加。眼球摘除到保存的时间间隔(BTO)没有缩短。新规则实施后角膜质量有所下降。

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