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[左侧肾上腺皮质癌伴肝转移及巨大腔静脉肿瘤血栓形成所致的库欣综合征]

[Cushing´s syndrome due to a left adrenal cortical carcinoma with metastasis to the liver and a massive vena cava tumor thrombus].

作者信息

Casallas Martha Alejandra, Calderón Carlos Mauricio

机构信息

Servicio de Medicina Interna, Universidad de La Sabana, Bogotá, D.C, Colombia.

出版信息

Biomedica. 2012 Oct-Dec;32(4):490-8. doi: 10.1590/S0120-41572012000400004.

DOI:10.1590/S0120-41572012000400004
PMID:23715224
Abstract

A 47-year-old woman with a seven-month history of increasing weight, hypertension and recently diagnosed diabetes presented features of hirsutism, frontal baldness, amenorrhea and hypokalemia. These characteristics were considered diagnostic of Cushing´s syndrome, and studies were initialized to identify its etiology. During hospitalization, the patient presented a torpid evolution resulting in death. Clinical autopsy revealed a 400 g carcinoma in the left adrenal gland, liver metastasis and a massive vena cava tumor thrombus which was the final cause of death.

摘要

一名47岁女性,有7个月体重增加、高血压病史,近期诊断为糖尿病,出现多毛、额部秃发、闭经和低钾血症。这些特征被认为是库欣综合征的诊断依据,于是启动了相关研究以确定其病因。住院期间,患者病情进展缓慢,最终死亡。临床尸检发现左肾上腺有一个400克的癌肿、肝转移以及巨大的腔静脉肿瘤血栓,这是死亡的最终原因。

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