Casallas Martha Alejandra, Calderón Carlos Mauricio
Servicio de Medicina Interna, Universidad de La Sabana, Bogotá, D.C, Colombia.
Biomedica. 2012 Oct-Dec;32(4):490-8. doi: 10.1590/S0120-41572012000400004.
A 47-year-old woman with a seven-month history of increasing weight, hypertension and recently diagnosed diabetes presented features of hirsutism, frontal baldness, amenorrhea and hypokalemia. These characteristics were considered diagnostic of Cushing´s syndrome, and studies were initialized to identify its etiology. During hospitalization, the patient presented a torpid evolution resulting in death. Clinical autopsy revealed a 400 g carcinoma in the left adrenal gland, liver metastasis and a massive vena cava tumor thrombus which was the final cause of death.
一名47岁女性,有7个月体重增加、高血压病史,近期诊断为糖尿病,出现多毛、额部秃发、闭经和低钾血症。这些特征被认为是库欣综合征的诊断依据,于是启动了相关研究以确定其病因。住院期间,患者病情进展缓慢,最终死亡。临床尸检发现左肾上腺有一个400克的癌肿、肝转移以及巨大的腔静脉肿瘤血栓,这是死亡的最终原因。