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采用纸片扩散法检测耐甲氧西林凝固酶阴性葡萄球菌(MRCoNS)

Methicillin-resistant coagulase-negative staphylococci (MRCoNS) by disk diffusion method.

作者信息

Rahman A, Hossain M A, Paul S K, Sultana S, Haque N, Kabir M R, Hoque S M

机构信息

Department of Microbiology, Northern (Pvt.) Medical College, Rangpur, Bangladesh.

出版信息

Mymensingh Med J. 2013 Apr;22(2):229-31.

Abstract

The antimicrobial susceptibility of 80 coagulase-negative staphylococci (CoNS) isolates from surgical wound, pus from infected skin lesions, burn exudates and diabetic ulcer exudates of patients in Mymensingh Medical College Hospital, Bangladesh, was evaluated in order to see their pattern of antimicrobial resistance. The study was carried out in the department of Microbiology, Mymensingh Medical College during the period from July 2009 to May 2011. The 80 CoNS isolates were subjected to antimicrobial susceptibility to relevant antibiotics including oxacillin by disk diffusion method. Out of 80 CoNS isolates, the highest number were resistant to oxacillin 36(45%), followed by gentamicin 32(40%), cefuroxime 25(31%), ceftriaxone 24(30%) and ciprofloxacin 18(22%). All isolates of CoNS were sensitive to imipenem and vancomycin. As MRCoNS were found multidrug resistant, therefore, antibiotic sensitivity must be done prior to treatment in infections caused by these species.

摘要

为了解孟加拉国迈门辛医学院医院患者手术伤口、感染性皮肤损伤脓液、烧伤渗出液及糖尿病溃疡渗出液中分离出的80株凝固酶阴性葡萄球菌(CoNS)的抗菌药敏情况,对其耐药模式进行了评估。该研究于2009年7月至2011年5月期间在迈门辛医学院微生物学系开展。采用纸片扩散法对80株CoNS分离株进行了包括苯唑西林在内的相关抗生素的药敏试验。在80株CoNS分离株中,对苯唑西林耐药的数量最多,为36株(45%),其次是庆大霉素32株(40%)、头孢呋辛25株(31%)、头孢曲松24株(30%)和环丙沙星18株(22%)。所有CoNS分离株对亚胺培南和万古霉素敏感。由于发现耐甲氧西林CoNS(MRCoNS)具有多重耐药性,因此,对于这些菌种引起的感染,在治疗前必须进行药敏试验。

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