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内耳黑色素对人类TTS易感性的影响。

The influence of inner ear melanin on susceptibility to TTS in humans.

作者信息

Barrenäs M L, Lindgren F

机构信息

Department of Audiology, Sahlgrenska Sjukhuset, Göteborg, Sweden.

出版信息

Scand Audiol. 1990;19(2):97-102. doi: 10.3109/01050399009070759.

DOI:10.3109/01050399009070759
PMID:2371541
Abstract

In order to investigate the function of the inner ear melanin, the relationship between skin pigmentation and noise-induced temporary hearing loss (TTS) was studied. Forty-four normal-hearing Caucasian subjects were divided into three groups according to their sun sensitivity. Hearing thresholds before and after exposure were ascertained with a computerized sweep frequency audiometer in the frequency range 2-8 kHz. The noise exposure consisted of a 1/3-octave band-filtered noise with a centre frequency of 2 kHz at 105 dB SPL for 10 min. The mean TTS in the frequency range 2-8 kHz showed statistically significant differences between the three groups, i.e. the most pigmented subjects developed least TTS, and the least pigmented subjects most TTS.

摘要

为了研究内耳黑色素的功能,对皮肤色素沉着与噪声性暂时性听力损失(TTS)之间的关系进行了研究。44名听力正常的白种人受试者根据其对阳光的敏感度分为三组。使用电脑扫频听力计在2 - 8kHz频率范围内确定暴露前后的听力阈值。噪声暴露为中心频率2kHz的1/3倍频程带通滤波噪声,声压级为105dB SPL,持续10分钟。2 - 8kHz频率范围内的平均TTS在三组之间显示出统计学上的显著差异,即色素沉着最多的受试者TTS最小,色素沉着最少的受试者TTS最大。

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