Departments of Radiology and Physical Medicine, Faculty of Medicine/Dentistry, University of Murcia, 30100, Espinardo (Murcia), Spain.
Radiol Med. 2013 Dec;118(8):1373-8. doi: 10.1007/s11547-013-0930-2. Epub 2013 May 27.
We evaluated the limitations of the ankle-brachial index (ABI) in the revascularisation of diabetic patients with critical limb ischaemia (CLI) who were undergoing peripheral transluminal angioplasty (PTA) compared with the degree of arterial stenosis and with transcutaneous oxygen tension (TcpO2).
This prospective study assessed 250 consecutive diabetic patients in whom we evaluated results of posterior tibial and dorsalis pedis Doppler, ABI, TcpO2, and duplex scans. In total, 104 patients were considered suitable candidates for PTA.
In 42% of the patients studied, ABI could either not be used (9.34% due to no signal; 14.02% because the artery could not be compressed) or was incorrect (18.7% before PTA; 15.9% after PTA). In contrast, TcpO2 was determined in all cases. After PTA, vessel stenosis decreased from 58.33±20.07% to 21.87±13.57% (p<0.001), whereas ABI increased from 0.79±0.57 to 0.95±0.47 (p<0.001) and TcpO2 from 27.37±10.40 mmHg to 38.23±10.25 mmHg (p<0.001). A statistical analysis revealed scant correlation between techniques (TcpO2 and ABI) (r=0.14).
ABI shows significant limitations for the diagnosing and treating CLI patients compared with TcpO2.
我们评估了踝肱指数(ABI)在接受外周经腔血管成形术(PTA)的糖尿病合并严重肢体缺血(CLI)患者再血管化中的局限性,与动脉狭窄程度和经皮氧分压(TcpO2)相比。
这项前瞻性研究评估了 250 例连续的糖尿病患者,我们评估了胫后和足背多普勒、ABI、TcpO2 和双功扫描的结果。共有 104 例患者被认为适合 PTA。
在研究的 42%患者中,ABI 要么无法使用(9.34%是因为没有信号;14.02%是因为动脉无法压缩),要么是错误的(PTA 前 18.7%;PTA 后 15.9%)。相比之下,所有病例均测定了 TcpO2。PTA 后,血管狭窄从 58.33±20.07%减少至 21.87±13.57%(p<0.001),ABI 从 0.79±0.57 增加至 0.95±0.47(p<0.001),TcpO2 从 27.37±10.40mmHg 增加至 38.23±10.25mmHg(p<0.001)。统计学分析显示,两种技术(TcpO2 和 ABI)之间相关性较差(r=0.14)。
ABI 在诊断和治疗 CLI 患者方面与 TcpO2 相比存在显著局限性。