Department of Pharmacology, Geetanjali Medical College, Udaipur, Rajasthan, India.
Indian J Pharmacol. 2013 Mar-Apr;45(2):117-20. doi: 10.4103/0253-7613.108279.
To study drug use pattern in patients of primary open angle glaucoma (POAG) and to analyze the cost of different anti-glaucoma medications.
This prospective study was carried in the glaucoma clinic of a tertiary care teaching hospital over a period of 9 months. The data collected for patients with POAG included the patient's demographic details and the drugs prescribed. Data were analyzed for drug use pattern and cost drugs used.
In a total 180 prescriptions (297 drugs) analyzed, most drugs (83.83%) were prescribed by topical route as eye drops. β blockers (93.88%) were found to be the most frequently prescribed for POAG. Timolol (82.22%) was the most frequently prescribed drug and timolol with acetazolamide (17.22%) was the most commonly prescribed drug combination. Fixed dose combinations constituted 26.66% of prescriptions. β blockers were found to be cheaper than other anti-glaucoma drugs while prostaglandins analogs were the costliest. Instructions about the route, frequency and duration of treatment were present in all prescriptions. However, instructions regarding instillation of eye drops were missing in all prescriptions.
研究原发性开角型青光眼（POAG）患者的药物使用模式，并分析不同抗青光眼药物的成本。
本前瞻性研究在一家三级教学医院的青光眼诊所进行，历时 9 个月。POAG 患者的数据包括患者的人口统计学细节和处方的药物。对药物使用模式和使用药物的成本进行了数据分析。
在分析的 180 份处方（297 种药物）中，大多数药物（83.83%）以眼药水的局部途径给药。β受体阻滞剂（93.88%）被发现是最常开的 POAG 药物。噻吗洛尔（82.22%）是最常开的药物，噻吗洛尔与乙酰唑胺（17.22%）是最常开的药物组合。固定剂量组合占处方的 26.66%。β受体阻滞剂比其他抗青光眼药物便宜，而前列腺素类似物则是最贵的。所有处方都有关于治疗途径、频率和持续时间的说明。然而，所有处方都缺少关于滴眼的说明。
