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[复合填充材料生物学性能评估:其溶血活性和细胞毒性指标的测定]

[Assessment of the biological properties of composite filling materials: determination of indices of their hemolytic activity and cytotoxicity].

作者信息

Chechina G N, Poiurivskaia I Ia, Lanina S Ia, Polikarpova S I, Volkova O N, Sedysheva I Iu, Podcherniaeva R Ia, Mel'nichenko E I

出版信息

Stomatologiia (Mosk). 1990 Mar-Apr;69(2):9-12.

PMID:2371747
Abstract

Rapid methods for determining the hemolytic activity in 10% suspension of human red cells and the cytotoxicity in human embryo fibroblast and HeLa cell cultures were used to assess the biological characteristics of some experimental composite filling materials and their foreign analogs. The results permit assessing the impact on the biological characteristics of individual components, of the entire composition, of the purity of the initial ingredients and their polymerization ability, this being valuable for the development of materials with the optimal characteristics.

摘要

采用快速方法测定人红细胞10%悬浮液中的溶血活性以及人胚胎成纤维细胞和HeLa细胞培养物中的细胞毒性,以评估一些实验性复合填充材料及其国外类似物的生物学特性。这些结果有助于评估单个成分、整个组合物、初始成分的纯度及其聚合能力对生物学特性的影响,这对于开发具有最佳特性的材料具有重要价值。

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